Dębska-Szmich Sylwia, Czernek Urszula, Krakowska Magdalena, Frąckowiak Marta, Zięba Agnieszka, Czyżykowski Rafał, Kulejewska Dominika, Potemski Piotr
Klinika Chemioterapii Nowotworów, Katedra Onkologii, Uniwersytet Medyczny w Łodzi.
Klinika Chemioterapii Nowotworów, Wojewódzki Szpital Specjalistyczny im. Kopernika w Łodzi.
Prz Menopauzalny. 2014 Mar;13(1):64-9. doi: 10.5114/pm.2014.41084. Epub 2014 Mar 10.
Synchronous cancers account for 0.7-1.8% of all gynecologic cancers. Among them, synchronous ovarian and endometrial cancers are predominant (40-53%). Patients with synchronous cancers have better prognosis than those with single disseminated cancer. We present 10 patients with synchronous ovarian and endometrial cancers who were treated at the Chemotherapy Department of the Medical University of Lodz in 2009-2013. The most often reported symptom of the disease was abnormal vaginal bleeding (6 patients). The range of the patients' age was 48-62 and the median age was 56. Five patients had stage I of ovarian cancer, single patients had stage IIA, IIB and IIIB, 2 patients had stage IIIC. Three patients had I, 5 - II, and 2 - III stage of endometrial cancer. All patients had endometrioid type of endometrial cancer, 7 of them had also the same histological type of ovarian cancer. All patients had adjuvant chemotherapy because of ovarian cancer, none of them had adjuvant radiotherapy. One patient was lost to follow up. For other patients a median follow up was 13 months (range: 3-53 months). One patient experienced relapse, all patients are alive. Synchronous ovarian and endometrial cancers are usually diagnosed at an earlier stage, have lower histological grade and better prognosis than single cancers. The most common histological type of both endometrial and ovarian cancers is endometrioid carcinoma. The first symptoms reported by our patients and the course of the disease were concordant with data from the literature.
同时性癌占所有妇科癌症的0.7 - 1.8%。其中，同时性卵巢癌和子宫内膜癌最为常见（40 - 53%）。同时性癌患者的预后比单发播散性癌患者更好。我们报告了2009年至2013年在罗兹医科大学化疗科接受治疗的10例同时性卵巢癌和子宫内膜癌患者。该疾病最常报告的症状是阴道异常出血（6例患者）。患者年龄范围为48 - 62岁，中位年龄为56岁。5例患者为卵巢癌I期，1例患者为IIA期、IIB期和IIIB期，2例患者为IIIC期。3例患者为子宫内膜癌I期，5例为II期，2例为III期。所有患者均为子宫内膜样型子宫内膜癌，其中7例卵巢癌组织学类型相同。所有患者因卵巢癌接受了辅助化疗，均未接受辅助放疗。1例患者失访。其他患者的中位随访时间为13个月（范围：3 - 53个月）。1例患者复发，所有患者均存活。同时性卵巢癌和子宫内膜癌通常在较早期被诊断，组织学分级较低，预后比单发癌更好。子宫内膜癌和卵巢癌最常见的组织学类型是子宫内膜样癌。我们患者报告的首发症状和疾病进程与文献数据一致。
