Ko Yeong-Mu, Choi Do-Young, Jung Sang-Chul, Kim Byung-Hoon
J Nanosci Nanotechnol. 2015 Jan;15(1):192-5. doi: 10.1166/jnn.2015.8372.
Polycaprolactone (PCL) nanofibers (PCL-NF) with uniform fibrous structure were fabricated by electrospinning. However, PCL-NF has hydrophobic surface, lacks functional groups and hence it is not a good substrate for cell adhesion. To improve the cell adhesion, PCL-NF surfaces were modified by low pressure RF discharge plasma treatment using monomer such as acrylic acid or oxygen gas. The plasma treated PCL-NFs improved the wettability and cell proliferation.
通过静电纺丝制备了具有均匀纤维结构的聚己内酯（PCL）纳米纤维（PCL-NF）。然而，PCL-NF具有疏水表面，缺乏官能团，因此它不是细胞黏附的良好基质。为了改善细胞黏附，使用丙烯酸或氧气等单体通过低压射频放电等离子体处理对PCL-NF表面进行了改性。经等离子体处理的PCL-NF提高了润湿性和细胞增殖能力。
