工程组织单跟踪位置剪切波弹性成像过程中的肖尔特波生成。
Scholte wave generation during single tracking location shear wave elasticity imaging of engineered tissues.
作者信息
Mercado Karla P, Langdon Jonathan, Helguera María, McAleavey Stephen A, Hocking Denise C, Dalecki Diane
机构信息
Department of Biomedical Engineering, Robert B. Georgen Hall, Box 270168, University of Rochester, Rochester, New York 14627, USA.
Chester F. Carlson Center for Imaging Science, 54 Lomb Memorial Drive, Rochester Institute of Technology, Rochester, New York 14623, USA.
出版信息
J Acoust Soc Am. 2015 Aug;138(2):EL138-44. doi: 10.1121/1.4927633.
Abstract
The physical environment of engineered tissues can influence cellular functions that are important for tissue regeneration. Thus, there is a critical need for noninvasive technologies capable of monitoring mechanical properties of engineered tissues during fabrication and development. This work investigates the feasibility of using single tracking location shear wave elasticity imaging (STL-SWEI) for quantifying the shear moduli of tissue-mimicking phantoms and engineered tissues in tissue engineering environments. Scholte surface waves were observed when STL-SWEI was performed through a fluid standoff, and confounded shear moduli estimates leading to an underestimation of moduli in regions near the fluid-tissue interface.
摘要
工程组织的物理环境会影响对组织再生至关重要的细胞功能。因此，迫切需要能够在制造和发育过程中监测工程组织力学性能的非侵入性技术。这项工作研究了使用单跟踪位置剪切波弹性成像（STL-SWEI）来量化组织工程环境中组织模拟体模和工程组织的剪切模量的可行性。当通过流体间隔进行STL-SWEI时观察到肖尔特表面波，这混淆了剪切模量估计，导致流体-组织界面附近区域的模量被低估。
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