来自高獐牙菜全草的呫吨酮及其抗烟草花叶病毒活性。
Xanthones from the herb of Swertia elata and their anti-TMV activity.
作者信息
Jiang Wei, Zhu Dong-Lai, Wang Ming-Feng, Yang Qing-Song, Zuo Ma-Yi, Zeng Liang, Li Gan-Peng
机构信息
a Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education , Yunnan Minzu University , Kunming , P.R. China.
b Technology Center , China Tobacco Yunnan Industry Company (Ltd.) , Kunming , P.R. China.
出版信息
Nat Prod Res. 2016 Aug;30(16):1810-5. doi: 10.1080/14786419.2015.1081198. Epub 2015 Sep 2.
Two new xanthones (1-2), together with four known ones (3-6), were isolated from whole herb of Swertia elata. Their structures were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques. Their anti-tobacco mosaic virus (anti-TMV) activity test revealed that 1-6 showed weak anti-TMV activities with inhibition rate in the range of 15.2-28.8% at the concentration of 20 μM.
从高獐牙菜全草中分离得到两个新的呫吨酮（1-2）以及四个已知的呫吨酮（3-6）。通过包括广泛的一维和二维核磁共振技术在内的光谱方法阐明了它们的结构。它们的抗烟草花叶病毒（抗TMV）活性测试表明，在20μM浓度下，1-6表现出较弱的抗TMV活性，抑制率在15.2-28.8%范围内。
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