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Cell and in vivo imaging of fluoride ion with highly selective bioluminescent probes.

作者信息

Ke Bowen, Wu Wenxiao, Wei Liu, Wu Fengbo, Chen Guo, He Gu, Li Minyong

机构信息

Department of Anaesthesiology and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University , Chengdu, Sichuan 610041, China.

Department of Medicinal Chemistry, Key Laboratory of Chemical Biology (MOE), School of Pharmacy, Shandong University , Jinan, Shandong 250012, China.

出版信息

Anal Chem. 2015 Sep 15;87(18):9110-3. doi: 10.1021/acs.analchem.5b02237. Epub 2015 Sep 3.

DOI:10.1021/acs.analchem.5b02237
PMID:26329828
Abstract

Two rapid bioluminescent probes for the detection of fluoride ion were developed on the basis of F-Si bond formation herein. It should be noted that probe 1 exhibited highly selective and sensitive detection toward fluoride ion over other anions and has been successfully applied in imaging fluoride ion in both living cells and animals.

摘要

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