浆细胞白血病伪装成桥本甲状腺炎时的同步甲状腺受累：辅助细胞学技术在诊断检查中的作用
Synchronous Thyroid Involvement in Plasma Cell Leukemia Masquerading as Hashimoto's Thyroiditis: Role of Ancillary Cytology Techniques in Diagnostic Workup.
作者信息
Tandon Ashwani, Paul T Roshni, Singh Rekha, Narendra A M V R
机构信息
Department of Pathology, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, 500082, India.
Department of Endocrinology and Metabolism, Nizam's Institute of Medical Sciences, Punjagutta, Hyderabad, India.
出版信息
Endocr Pathol. 2015 Dec;26(4):324-7. doi: 10.1007/s12022-015-9392-5.
Neoplastic plasma cell involvement of thyroid is an uncommon condition, and it may involve thyroid in multiple myeloma or solitary plasmacytoma. Its clinical and pathological features are not well understood. We present a rare case of synchronous thyroid involvement in plasma cell leukemia presenting as thyroid nodule with primary hypothyroidism. Simultaneous cytology, immunocytochemistry, FISH analysis with 13q14.3 and TP53 on cytology smears and haematology workup were performed to diagnose and to understand disease pathobiology with poor outcome.
甲状腺的肿瘤性浆细胞浸润是一种罕见的情况，它可能在多发性骨髓瘤或孤立性浆细胞瘤中累及甲状腺。其临床和病理特征尚未完全明确。我们报告了一例罕见的浆细胞白血病同步累及甲状腺的病例，表现为甲状腺结节伴原发性甲状腺功能减退。同时进行了细胞学检查、免疫细胞化学、对细胞学涂片进行13q14.3和TP53的荧光原位杂交分析以及血液学检查，以进行诊断并了解疾病的病理生物学情况，该病例预后较差。
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