Martínez-Gómez D, Guallar-Castillon P, Mota J, Lopez-Garcia E, Rodriguez-Artalejo F
Department of Physical Education, Sport and Human Movement, Faculty of Teacher Training and Education, Universidad Autónoma de Madrid, Madrid, Spain.
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid/IdiPaz, Madrid, Spain, CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Int J Sports Med. 2015 Dec;36(14):1206-11. doi: 10.1055/s-0035-1555860. Epub 2015 Sep 2.
The purpose of this study was to examine the independent and combined association of physical activity (PA) and sitting time (ST) with all-cause mortality in older adults with diabetes. A total of 611 individuals representative of the Spanish diabetic population aged ≥ 60 years. Participants were selected in 2000/2001 and were prospectively followed-up through 2011. PA and ST were self-reported at baseline. Study associations were summarized as hazard ratios (HR) and their 95% confidence interval (CI). During a mean follow-up of 8.3 years, 282 deaths occurred. The HR (95% CI) of mortality for very/moderately active individuals compared to those who were inactive/less active was 0.59 (0.45, 0.78). The association between ST and mortality was non-linear (P<0.001 in spline analysis), and mortality was increased only among individuals who reported a ST>8 h/day (HR=1.77, 95% CI 1.25, 2.52). The HR (95% CI) of mortality was 0.50 (0.32, 0.77) in participants who either were very/moderately active or had ST≤8 h/day, and 0.32 (0.20, 0.50) in those with both health behaviors, compared to those with none of these behaviors. In conclusion, among older adults with diabetes, high PA and less ST are independently and jointly associated with lower risk of all-cause mortality.
本研究的目的是探讨身体活动（PA）和久坐时间（ST）与老年糖尿病患者全因死亡率之间的独立关联和联合关联。共有611名年龄≥60岁的西班牙糖尿病患者作为代表性个体。参与者于2000/2001年入选，并前瞻性随访至2011年。PA和ST在基线时通过自我报告获得。研究关联以风险比（HR）及其95%置信区间（CI）进行总结。在平均8.3年的随访期间，发生了282例死亡。与不活动/活动较少的个体相比，非常活跃/中度活跃个体的死亡HR（95%CI）为0.59（0.45，0.78）。ST与死亡率之间的关联是非线性的（样条分析中P<0.001），且仅在报告ST>8小时/天的个体中死亡率增加（HR=1.77，95%CI 1.25，2.52）。与没有这些健康行为的个体相比，要么非常活跃/中度活跃要么ST≤8小时/天的参与者的死亡HR（95%CI）为0.50（0.32，0.77），而同时具备这两种健康行为的个体的死亡HR（95%CI）为0.32（0.20，0.50）。总之，在老年糖尿病患者中，高身体活动水平和较少的久坐时间与较低的全因死亡风险独立且共同相关。
