Martínez-Gómez David, Guallar-Castillón Pilar, León-Muñoz Luz M, Rodríguez-Artalejo Fernando
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain; IdiPAZ-CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Department of Preventive Medicine and Public Health, School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain; IdiPAZ-CIBER of Epidemiology and Public Health (CIBERESP), Madrid, Spain.
Prev Med. 2014 Apr;61:14-9. doi: 10.1016/j.ypmed.2014.01.006. Epub 2014 Jan 15.
To examine the association between household physical activity (HPA) and all-cause mortality in a cohort of older adults from Spain, and the role of sedentary time on this association.
Prospective cohort study of 2874 individuals aged ≥ 62 years. In 2003, the time spent in HPA and the time spent seated were self-reported. The association of HPA with all-cause mortality through 2011 was assessed with Cox regression.
During the follow-up, 970 participants died. In men, HPA was inversely associated with the risk of death only among those with longer sitting time (≥ 8 h/d): compared to those who did not do HPA, the mortality hazard ratio (HR) was 0.80 (95% confidence interval (CI): 0.60-1.08) and 0.43 (95% CI: 0.27-0.69) for those who spent >0 to 2h/d and >2h/d in HPA, respectively (P for trend<0.001). In women, sitting time did not modify the study association. Thus, compared to women who spent <2h/d in HPA, the HR for mortality was 0.72 (95% CI: 0.56-0.93) and 0.52 (95% CI: 0.39-0.70) for those who spent >2 to 4h/d, and >4h/d in HPA, respectively (P for trend<0.001).
In women, HPA is associated with reduced mortality regardless of sitting time. HPA may also contribute to longer survival among men with longer sitting time.
研究西班牙老年人群队列中家庭体力活动（HPA）与全因死亡率之间的关联，以及久坐时间在此关联中的作用。
对2874名年龄≥62岁的个体进行前瞻性队列研究。2003年，通过自我报告获取HPA时间和久坐时间。采用Cox回归评估HPA与截至2011年的全因死亡率之间的关联。
随访期间，970名参与者死亡。在男性中，仅在久坐时间较长（≥8小时/天）的人群中，HPA与死亡风险呈负相关：与未进行HPA的人群相比，每天进行HPA时间>0至2小时和>2小时的人群的死亡风险比（HR）分别为0.80（95%置信区间（CI）：0.60 - 1.08）和0.43（95%CI：0.27 - 0.69）（趋势P<0.001）。在女性中，久坐时间并未改变该研究关联。因此，与每天进行HPA时间<2小时的女性相比，每天进行HPA时间>2至4小时和>4小时的女性的死亡HR分别为0.72（95%CI：0.56 - 0.93）和0.52（95%CI：0.39 - 0.70）（趋势P<0.001）。
在女性中，无论久坐时间如何，HPA都与死亡率降低相关。HPA也可能有助于久坐时间较长的男性延长生存期。
