Le Nguyen Bao Khanh, Tran Thuy Nga, Nguyen Huu Chinh, Khouw Ilse, Deurenberg Paul
National Institute of Nutrition (NIN), Vietnam
National Institute of Nutrition (NIN), Vietnam.
Asia Pac J Public Health. 2016 Jul;28(5 Suppl):94S-102S. doi: 10.1177/1010539516641506. Epub 2016 Apr 6.
In a population sample of 385 children, 6 to 11 years old, venous blood parameters-hemoglobin (Hb), ferritin, red blood cell count (RBC), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), C-reactive protein (CRP), and α1-acid glycoprotein (AGP)-were determined to get insight into the iron status. The prevalence of anemia was 11.4%; 5.6% had iron deficiency (ID), whereas 0.4% had ID anemia. Correction for inflammation based on CRP and AGP did not markedly change the overall prevalence of ID and ID anemia. Stunted children had lower Hb and ferritin values compared with nonstunted children, and thin children had lower values compared with normal-weight or overweight and obese children. Many nonanemic children had alert values for RBC, MCV, MCH, and MCHC. It is concluded that although the prevalence of anemia is of the magnitude of a mild public health problem, the iron status of many nonanemic children is borderline, as indicated by a high number of children with low values for red blood cytology.
在一个包含385名6至11岁儿童的人群样本中,测定了静脉血参数——血红蛋白(Hb)、铁蛋白、红细胞计数(RBC)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)、C反应蛋白(CRP)和α1-酸性糖蛋白(AGP),以深入了解铁状态。贫血患病率为11.4%;5.6%患有缺铁(ID),而0.4%患有缺铁性贫血。基于CRP和AGP进行炎症校正后,ID和ID贫血的总体患病率没有明显变化。与非发育迟缓儿童相比,发育迟缓儿童的Hb和铁蛋白值较低,与正常体重、超重和肥胖儿童相比,消瘦儿童的值较低。许多非贫血儿童的RBC、MCV、MCH和MCHC值处于临界状态。结论是,尽管贫血患病率处于轻度公共卫生问题的程度,但许多非贫血儿童的铁状态处于临界水平,这表现为大量儿童的红细胞细胞学值较低。