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体外循环下不停跳冠状动脉血运重建:它对急诊血运重建有效吗?

On-pump beating heart coronary revascularization: Is it valid for emergency revascularization?

作者信息

Aydin Ahmet, Erkut Bilgehan

机构信息

Bilgehan Erkut, Prof, MD, Cardiovascular Surgery,, Erzincan University Medical Faculty,, Gazi Mengücek Training and Research Hospital,, 24000, Erzincan, Turkey, T: + 90 533 7451006, F: + 90 442 2326405,

出版信息

Ann Saudi Med. 2015 Mar-Apr;35(2):133-7. doi: 10.5144/0256-4947.2015.133.

DOI:10.5144/0256-4947.2015.133
PMID:26336019
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6074131/
Abstract

BACKGROUND

On-pump beating heart coronary artery bypass grafting (CABG) may be considered as an alternative to the conventional on-pump surgery in patients presenting with acute coronary syndrome requiring emergency revascularization. This study reports our clinical experience and early outcomes with the on-pump beating heart coronary surgery on patients with acute coronary syndrome.

DESIGN AND SETTINGS

A retrospective study conducted from August 2009 to October 2015, in a regional training and research hospital in Turkey.

METHODS

A total of 1432 patients underwent isolated CABG at our institution. A total of 316 of these patients underwent the on-pump beating heart procedure without cardioplegic arrest by the same surgeon.

RESULTS

The time interval from the onset of acute myocardial infarction to CABG was 10 (2.2) hours. The mean number of grafts was 3.0 (0.6). Hospital mortality was 2.9% (9 patients). Twelve patients had low cardiac output syndromes after surgery. Eight of them had renal dysfunction but none of them needed hemodialysis. The mean intensive care unit stay was 3 (2) days and the mean hospital length of stay was 7 (4) days.

CONCLUSION

We think that the on-pump beating heart revascularization technique can be a good choice for emergency CABG of high-risk patients with a multivessel coronary artery disease.

摘要

背景

对于患有急性冠状动脉综合征需要紧急血运重建的患者,体外循环心脏不停跳冠状动脉搭桥术(CABG)可被视为传统体外循环手术的一种替代方法。本研究报告了我们对急性冠状动脉综合征患者进行体外循环心脏不停跳冠状动脉手术的临床经验和早期结果。

设计与地点

2009年8月至2015年10月在土耳其一家地区培训和研究医院进行的一项回顾性研究。

方法

共有1432例患者在我们机构接受了单纯CABG手术。其中316例患者由同一位外科医生进行了体外循环心脏不停跳手术,未使用心脏停搏液。

结果

从急性心肌梗死发作到CABG的时间间隔为10(2.2)小时。平均移植血管数量为3.0(0.6)支。医院死亡率为2.9%(9例患者)。12例患者术后出现低心排血量综合征。其中8例有肾功能不全,但均无需血液透析。重症监护病房平均住院时间为3(2)天,平均住院时间为7(4)天。

结论

我们认为,体外循环心脏不停跳血运重建技术对于多支冠状动脉疾病的高危患者进行急诊CABG可能是一个不错的选择。

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本文引用的文献

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On-pump versus off-pump surgical revascularization in patients with acute coronary syndromes: analysis from the Acute Catheterization and Urgent Intervention Triage Strategy trial.在急性冠状动脉综合征患者中进行体外循环与非体外循环冠状动脉旁路移植术:来自急性导管插入术和紧急介入治疗分诊策略试验的分析。
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Emergency coronary artery bypass graft surgery for acute coronary syndrome: beating heart versus conventional cardioplegic cardiac arrest strategies.急性冠状动脉综合征的急诊冠状动脉旁路移植手术:心脏不停跳与传统心脏停搏策略对比
Circulation. 2006 Jul 4;114(1 Suppl):I477-85. doi: 10.1161/CIRCULATIONAHA.105.001545.
3
On-pump beating heart versus off-pump coronary artery bypass surgery-evidence of pump-induced myocardial injury.心脏不停跳与非体外循环冠状动脉搭桥手术——体外循环导致心肌损伤的证据
Eur J Cardiothorac Surg. 2005 Jun;27(6):1057-64. doi: 10.1016/j.ejcts.2005.03.007. Epub 2005 Apr 8.
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ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery).美国心脏病学会/美国心脏协会冠状动脉搭桥手术2004年指南更新:美国心脏病学会/美国心脏协会实践指南工作组(更新1999年冠状动脉搭桥手术指南委员会)报告
Circulation. 2004 Oct 5;110(14):e340-437.
5
Systematic organ protection in coronary artery surgery with or without cardiopulmonary bypass.冠状动脉手术中有无体外循环时的系统性器官保护
J Card Surg. 2002 Nov-Dec;17(6):529-35. doi: 10.1046/j.1540-8191.2002.01010.x.
6
Myocardial infarction in coronary bypass surgery using on-pump, beating heart technique with pressure- and volume-controlled coronary perfusion.在冠状动脉搭桥手术中使用体外循环、心脏跳动技术并进行压力和容量控制的冠状动脉灌注时发生的心肌梗死。
J Card Surg. 2002 Jul-Aug;17(4):272-8. doi: 10.1111/j.1540-8191.2001.tb01139.x.
7
A risk model derived from the National Registry of Myocardial Infarction 2 database for predicting mortality after coronary artery bypass grafting during acute myocardial infarction.一种源自心肌梗死国家注册数据库2的风险模型,用于预测急性心肌梗死期间冠状动脉旁路移植术后的死亡率。
Am J Cardiol. 2002 Jul 1;90(1):1-4. doi: 10.1016/s0002-9149(02)02375-5.
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J Card Surg. 2000 Nov-Dec;15(6):403-10. doi: 10.1111/j.1540-8191.2000.tb01300.x.
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Emergency myocardial revascularization for acute myocardial infarction: survival benefits of avoiding cardiopulmonary bypass.急性心肌梗死的急诊心肌血运重建:避免体外循环的生存获益
Eur J Cardiothorac Surg. 2000 Mar;17(3):234-8. doi: 10.1016/s1010-7940(00)00354-7.