心脏磁共振成像确诊的美沙拉嗪诱发的心肌炎。
Cardiac MRI-confirmed mesalamine-induced myocarditis.
作者信息
Baker William L, Saulsberry Whitney J, Elliott Kaitlyn, Parker Matthew W
机构信息
Department of Pharmacy Practice, University of Connecticut School of Pharmacy, Storrs, Connecticut, USA.
Department of Cardiology, Hartford Hospital, Hartford, Connecticut, USA.
出版信息
BMJ Case Rep. 2015 Sep 4;2015:bcr2015210689. doi: 10.1136/bcr-2015-210689.
A 38-year-old Caucasian man with a medical history significant for inflammatory bowel disease (IBD) and mesalamine use presented to the emergency department with stabbing, pleuritic, substernal chest pain over the previous 2 days. Findings of leucocytosis, elevated cardiac enzymes and inflammatory markers, T-wave or ST-segment abnormalities and left ventricular systolic dysfunction suggested mesalamine-induced myocarditis. However, a cardiac MRI confirmed the diagnosis. Signs and symptoms improved within days of withdrawal of mesalamine, and initiation of corticosteroids and follow-up studies within the next year were unremarkable. Importantly, the diagnosis of mesalamine-induced myocarditis confirmed via cardiac MRI is a step rarely performed in published cases.
一名38岁的白人男性，有炎症性肠病（IBD）病史且曾使用美沙拉嗪，在过去2天出现刺痛性、胸膜炎性、胸骨后胸痛，遂前往急诊科就诊。白细胞增多、心肌酶和炎症标志物升高、T波或ST段异常以及左心室收缩功能障碍等检查结果提示为美沙拉嗪诱发的心肌炎。然而，心脏磁共振成像（MRI）确诊了该疾病。停用美沙拉嗪数天内，症状体征有所改善，随后开始使用皮质类固醇，且次年的随访研究结果无异常。重要的是，通过心脏MRI确诊美沙拉嗪诱发的心肌炎这一诊断步骤在已发表的病例中很少进行。
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