Clinical and Experimental Department, Sports Medicine Center, University of Florence, Florence, Italy.
Division of Nephrology, University Hospital Careggi, Florence, Italy.
Intern Emerg Med. 2016 Feb;11(1):61-7. doi: 10.1007/s11739-015-1294-5. Epub 2015 Sep 4.
Regular physical exercise plays a role in improving cardiovascular and muscular fitness in many metabolic diseases. This study aims to verify any possible benefits, including the eventual influence on any associated risk factors, in a group of kidney transplant recipients after a short period of personalized training programs with mixed exercises. In January 2013, at the Sports Medicine Center of the University of Florence, Italy, we began studying a group of 20 kidney transplant recipients. After 6 months of exercise, they underwent Cardiopulmonary Test (CPET), ECG, skin fold, bioimpedance analysis and stress test for the lower and upper limbs. EF increased significantly from 63.38 ± 4 to 67.30 ± 5.9 with p < 0.05; the anaerobic threshold improved from 14.48 ± 6.3 to 20.24 ± 3.7 (p < 0.05) with good stress tolerance, estimated by CR10 scale; weight decreased significantly (70.06-65.03 kg) as did skin folds at pectoral level (p < 0.002). Upper limb muscular strength increased significantly (p < 0.005). Regular mixed exercise is a proposed program in post-transplant syndrome with the expectation of improving cardiovascular performance and enhancing exercise tolerance. Muscle strength improves with physical fitness with consequent reduction of risk factors linked to visceral fat. Proof of an eventual positive impact on other complex aspects associated with post-transplant metabolic syndrome will require a longer follow-up.
定期进行体育锻炼对改善多种代谢疾病的心血管和肌肉健康起着重要作用。本研究旨在验证在一组接受过短期个性化混合运动训练计划的肾移植受者中,这种锻炼可能带来的任何益处,包括对任何相关风险因素的最终影响。2013 年 1 月,在意大利佛罗伦萨大学运动医学中心,我们开始对 20 名肾移植受者进行研究。经过 6 个月的运动后,他们接受了心肺测试(CPET)、心电图、皮褶厚度、生物阻抗分析和上下肢压力测试。EF 从 63.38 ± 4 显著增加到 67.30 ± 5.9,p 值<0.05;无氧阈从 14.48 ± 6.3 提高到 20.24 ± 3.7(p 值<0.05),同时 CR10 量表评估的应激耐受力良好;体重显著下降(从 70.06 降至 65.03kg),胸皮褶厚度也显著下降(p 值<0.002)。上肢肌肉力量显著增加(p 值<0.005)。定期进行混合运动是一种针对移植后综合征的推荐方案,期望能改善心血管功能并提高运动耐受力。随着身体适应性的提高,肌肉力量也会增强,从而降低与内脏脂肪相关的风险因素。要证明其对与移植后代谢综合征相关的其他复杂方面的最终积极影响,需要更长时间的随访。