Orlandi Goffredo, Sofi Francesco, Moscarelli Luciano, Cirami Lino, Mancini Sabrina, Stefani Laura
Sports Medicine and Exercise Unit, Department of Experimental and Clinical Medicine, University of Florence, 50141 Florence, Italy.
Unit of Clinical Nutrition, Department of Experimental and Clinical Medicine, University of Florence, 50141 Florence, Italy.
J Funct Morphol Kinesiol. 2020 Jan 30;5(1):10. doi: 10.3390/jfmk5010010.
Renal transplantation is the choice treatment for end-stage renal disease. In spite of transplantation, cardiovascular morbidity and mortality remains high, possibly due to a prolonged sedentary lifestyle prior to transplantation. This study aimed to evaluate the impact of unsupervised intervention in a tailored home-based aerobic resistance exercise program, based on the anthropometric and cardiovascular parameters in a group of renal transplant recipients (RTRs) followed for 12 months.
a group of 21 RTRs (mean age: 46.8 ± 12 years) were enrolled in a combined aerobic and step count unsupervised prescription program. Body composition (BMI, waist circumferences, skin-folds); water distribution (TBW: Total body water; ECW: Extra cellular water; and ICW: Intracellular water) and myocardial function were measured every 6 months for 1 year. The MEDI-LITE score was used to estimate adherence to the Mediterranean diet.
Significant reductions in waist circumference (Waist Cir: 89.12 ± 12.8 cm T0; 89.1 ± 12.5 cm T6 (95% CI: 6.3, 5.7); 88.6 ± 11.4 cm T12; (95% CI: 6.7, 4.7) < 0.01), weight:71.8 ± 14.8 kg T0; 70.6 ± 14.7 kg T6(95% CI:-8, 6); 70.6 ± 14.7 kg T12(95% CI: 6.6, 7) < 0.05), as well as an improvement of myocardial function, as shown by the significant increase of contractility and change in the GLS % value (-18.3 ± 3.8% at T0 (95% CI:-16.57, 20.0.2)-20.4 ± 3.0% at T6(95% CI:-4, 0.2);-22.9 ± 3.1%T12(95% CI:-3, 4, -1, 6) < 0.02), were observed. Adherence to the Mediterranean diet was in the normal range.
Despite unsupervised intervention, combined moderate physical exercise appears to have a positive effect on the main parameters related to cardiovascular risk factors. The long-term efficacy of this program requires further investigation, particularly for evaluating constant adherence to the home-based physical exercise program.
肾移植是终末期肾病的首选治疗方法。尽管进行了移植，但心血管疾病的发病率和死亡率仍然很高，这可能是由于移植前长期久坐的生活方式所致。本研究旨在基于一组接受随访12个月的肾移植受者（RTRs）的人体测量和心血管参数，评估在量身定制的家庭有氧抗阻运动计划中进行无监督干预的影响。
一组21名RTRs（平均年龄：46.8±12岁）参加了一项有氧和步数计数相结合的无监督处方计划。在1年的时间里，每6个月测量一次身体成分（BMI、腰围、皮褶厚度）；水分分布（TBW：总体水；ECW：细胞外水；ICW：细胞内水）和心肌功能。使用MEDI-LITE评分来评估对地中海饮食的依从性。
腰围显著减小（腰围：T0时89.12±12.8cm；T6时89.1±12.5cm（95%CI：6.3，5.7）；T12时88.6±11.4cm；（95%CI：6.7，4.7）<0.01），体重：T0时71.8±14.8kg；T6时70.6±14.7kg（95%CI：-8，6）；T12时70.6±14.7kg（95%CI：6.6，7）<0.05），心肌功能也有所改善，表现为收缩力显著增加和GLS%值变化（T0时为-18.3±3.8%（95%CI：-16.57，20.0.2）；T6时为-20.4±3.0%（95%CI：-4，0.2）；T12时为-22.9±3.1%（95%CI：-3，4，-1，6）<0.02）。对地中海饮食的依从性处于正常范围。
尽管是无监督干预，但适度的体育锻炼组合似乎对与心血管危险因素相关的主要参数有积极影响。该计划的长期疗效需要进一步研究，特别是用于评估对家庭体育锻炼计划的持续依从性。
