Moscarelli Luciano, Sofi Francesco, Mascherini Gabriele, Bini Vittorio, Ingletto Chiara, Mandoli Marco, Galanti Giorgio, Stefani Laura
Nephrology Unit, University Hospital Careggi, 50139 Florence, Italy.
Department of Experimental and Clinical Medicine, Unit of Clinical Nutrition, University of Florence, 50139 Florence, Italy.
J Funct Morphol Kinesiol. 2018 Sep 11;3(3):46. doi: 10.3390/jfmk3030046.
Renal transplant recipients (RTRs) are at high cardiovascular risk (CV) compared to the general population, especially after surgical treatment. The literature supports the role of supervised exercise intervention; however no data are available regarding the effects of unsupervised exercise programs. We investigated whether a home exercise program could reduce CV risk in RTR based on possible changes in renal and cardiometabolic parameters and myocardial performance measured by echocardiography.
From a large cohort of 60 RTRs, 30 RTRs (12 females and 18 males 48.3 ± 12.3 years) participated in individualized and unsupervised training programs for 6 months, at moderate intensity. Cardiometabolic risk factors, anthropometric parameters, lipid and glycemic blood sample profiles were studied as was myocardial performance from the 2D echo examination at T0, and T6 months.
The lipid profile remained in the range of a low level of risk, although there was no significant improvement, whereas myocardial performance, in particular the EF, was significantly improved.
A home exercise program for at least 6 months produces positive effects on myocardial function and helps maintain a low cardiovascular risk profile. The trend supports the importance of highlighting the role of a correct reconditioning of lifestyle in RTR, from the exercise program without supervision to moderate intensity, where well tolerated.
与普通人群相比,肾移植受者(RTR)面临较高的心血管风险(CV),尤其是在接受手术治疗后。文献支持有监督的运动干预的作用;然而,关于无监督运动计划的效果尚无数据。我们基于肾和心脏代谢参数以及超声心动图测量的心肌性能的可能变化,研究了家庭运动计划是否可以降低RTR的心血管风险。
从60名RTR的大型队列中,30名RTR(12名女性和18名男性,年龄48.3±12.3岁)参加了为期6个月的个体化且无监督的中等强度训练计划。研究了心脏代谢危险因素、人体测量参数、血脂和血糖血样概况,以及在T0和T6个月时二维超声心动图检查的心肌性能。
尽管没有显著改善,但血脂水平仍处于低风险范围内,而心肌性能,特别是射血分数(EF),有显著改善。
至少6个月的家庭运动计划对心肌功能产生积极影响,并有助于维持低心血管风险状况。这一趋势支持了强调正确调整生活方式在RTR中的作用的重要性,从无监督的运动计划到中等强度且耐受性良好的运动计划。