Hardt Karin, Schmidt-Ott Ruprecht, Glismann Steffen, Adegbola Richard A, Meurice François P
GlaxoSmithKline Vaccines, Global Scientific Affairs & Medical Education, 20 Avenue Fleming, 1300 Wavre, Belgium.
GlaxoSmithKline Vaccines, Global Scientific Affairs & Medical Education, Prinzregentenplatz 9, 81675 Munich, Germany.
Vaccines (Basel). 2013 Jun 24;1(3):204-24. doi: 10.3390/vaccines1030204.
Vaccination provides many health and economic benefits to individuals and society, and public support for immunization programs is generally high. However, the benefits of vaccines are often not fully valued when public discussions on vaccine safety, quality or efficacy arise, and the spread of misinformation via the internet and other media has the potential to undermine immunization programs. Factors associated with improved public confidence in vaccines include evidence-based decision-making procedures and recommendations, controlled processes for licensing and monitoring vaccine safety and effectiveness and disease surveillance. Community engagement with appropriate communication approaches for each audience is a key factor in building trust in vaccines. Vaccine safety/quality issues should be handled rapidly and transparently by informing and involving those most affected and those concerned with public health in effective ways. Openness and transparency in the exchange of information between industry and other stakeholders is also important. To maximize the safety of vaccines, and thus sustain trust in vaccines, partnerships are needed between public health sector stakeholders. Vaccine confidence can be improved through collaborations that ensure high vaccine uptake rates and that inform the public and other stakeholders of the benefits of vaccines and how vaccine safety is constantly assessed, assured and communicated.
疫苗接种为个人和社会带来诸多健康和经济效益，公众对免疫规划的支持总体较高。然而，当公众讨论疫苗安全、质量或效力时，疫苗的益处往往未得到充分重视，通过互联网和其他媒体传播的错误信息有可能破坏免疫规划。与提高公众对疫苗的信心相关的因素包括基于证据的决策程序和建议、疫苗许可及监测安全性和有效性的受控流程以及疾病监测。针对不同受众采用适当的沟通方式进行社区参与是建立对疫苗信任的关键因素。疫苗安全/质量问题应以有效方式告知并让受影响最大的人群及关注公共卫生的人群参与其中，从而迅速且透明地加以处理。行业与其他利益相关者之间信息交流的公开性和透明度也很重要。为了最大限度提高疫苗安全性，进而维持对疫苗的信任，公共卫生部门的利益相关者之间需要建立伙伴关系。通过合作可提高疫苗信心，这些合作能确保高疫苗接种率，并向公众和其他利益相关者宣传疫苗的益处以及疫苗安全性是如何持续评估、确保和传达的。
