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未来十年的疫苗安全:为何我们需要建立信任的新模式。

Vaccine safety in the next decade: why we need new modes of trust building.

作者信息

Larson Heidi J, Sahinovic Isabelle, Balakrishnan Madhava Ram, Simas Clarissa

机构信息

Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK

World Health Organization, Geneve, Switzerland.

出版信息

BMJ Glob Health. 2021 May;6(Suppl 2). doi: 10.1136/bmjgh-2020-003908.

DOI:10.1136/bmjgh-2020-003908
PMID:34011503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8137162/
Abstract

Among the realm of highly varied vaccine perceptions and concerns expressed by publics around the world, vaccine safety is the most frequently cited. While many of the safety questions raised have substantial evidence to address the concerns, vaccines do have small risks, and need vigilant and responsive systems to address them. With more and more new vaccines, combinations of vaccines and new technologies to develop and deliver them, new safety concerns will arise that need attention. Adding to this landscape is the dramatic impact which digital communication has had on how fast rumours and vaccine concerns can spread, making the task of the public health and scientific community even more pressing. One of the more recently characterised vaccine safety issues, now named 'immunisation stress-related-response,' has gained particularly high visibility given these highly globally connected social media networks. To better anticipate and address these rapidly shared vaccine safety concerns, a number of global efforts and local responses are being made. Co-created social media campaigns engaging parents and adolescents have been effective, while the WHO's Vaccine Safety Net (VSN) initiative has grown its global network to increase awareness about vaccines and contribute to building confidence in vaccines. The VSN reviews websites around the world to assess their quality and accuracy to ensure and promote access to trustworthy and science-based information on vaccine safety for internet users. These and the efforts of the multiple network partners are more crucial than ever to sustain public confidence in this evolving vaccine safety landscape.

摘要

在世界各地公众表达的各种各样的疫苗认知和担忧中,疫苗安全是最常被提及的。虽然提出的许多安全问题都有大量证据来解决这些担忧,但疫苗确实存在小风险,需要有警惕且响应迅速的系统来应对。随着越来越多的新疫苗、疫苗组合以及用于研发和交付它们的新技术出现,将会出现需要关注的新安全问题。此外,数字通信对谣言和疫苗担忧的传播速度产生了巨大影响,这使得公共卫生和科学界的任务更加紧迫。鉴于这些高度全球化的社交媒体网络,最近被描述的一个疫苗安全问题,现在被称为“免疫应激相关反应”,已经获得了特别高的关注度。为了更好地预测和应对这些迅速传播的疫苗安全担忧,正在开展一些全球努力和地方应对措施。与家长和青少年共同开展的社交媒体活动很有效,而世卫组织的疫苗安全网(VSN)倡议扩大了其全球网络,以提高对疫苗的认识,并有助于建立对疫苗的信心。VSN对世界各地的网站进行审查,以评估其质量和准确性,确保并促进互联网用户获取关于疫苗安全的可靠且基于科学的信息。在这个不断演变的疫苗安全格局中,这些以及多个网络合作伙伴的努力对于维持公众信心比以往任何时候都更加关键。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd86/8137162/404b4ebb828b/bmjgh-2020-003908f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd86/8137162/404b4ebb828b/bmjgh-2020-003908f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd86/8137162/404b4ebb828b/bmjgh-2020-003908f01.jpg

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本文引用的文献

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Mapping global trends in vaccine confidence and investigating barriers to vaccine uptake: a large-scale retrospective temporal modelling study.绘制全球疫苗信心趋势图并调查疫苗接种障碍:一项大规模回顾性时间建模研究。
Lancet. 2020 Sep 26;396(10255):898-908. doi: 10.1016/S0140-6736(20)31558-0. Epub 2020 Sep 10.
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Immunization stress-related response - Redefining immunization anxiety-related reaction as an adverse event following immunization.免疫接种相关应激反应 - 将免疫接种焦虑相关反应重新定义为免疫接种后不良事件。
Vaccine. 2020 Mar 23;38(14):3015-3020. doi: 10.1016/j.vaccine.2020.02.046. Epub 2020 Mar 2.
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The science of vaccine safety: Summary of meeting at Wellcome Trust.
父母对人乳头瘤病毒疫苗接种推广信息及沟通方式的偏好是什么?离散选择实验在法属加勒比地区的应用。
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Using social media to build confidence in vaccines: lessons from community engagement and social science research in Africa.利用社交媒体建立疫苗信心:非洲社区参与和社会科学研究的经验教训。
BMJ. 2024 Jan 16;384:e075564. doi: 10.1136/bmj-2023-075564.
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Pervasive Parental Hesitancy and Resistance towards Measles Rubella Vaccination in Jordan.约旦父母对麻疹风疹疫苗接种普遍存在犹豫和抵触情绪。
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Towards a More Critical Public Health Understanding of Vaccine Hesitancy: Key Insights from a Decade of Research.迈向对疫苗犹豫更具批判性的公共卫生理解:十年研究的关键见解
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