Esposito Marco, Barausse Carlo, Pistilli Roberto, Sammartino Gilberto, Grandi Giovanni, Felice Pietro
Eur J Oral Implantol. 2015 Autumn;8(3):257-68.
To evaluate whether short (5.0 to 8.5 mm) dental implants could be a suitable alternative to longer (at least 11.5 mm-long) implants placed in atrophic maxillae augmented with autogenous bone for supporting dental prostheses.
Twenty-eight patients with fully edentulous atrophic maxillae, whom had 5 to 9 mm of residual crestal bone height which was at least 5 mm thick, measured using computerised tomography (CT) scans, were randomised into two groups either to receive 4 to 8 short (5.0 to 8.5 mm) implants (15 patients) or autogenous bone from the iliac crest to allow the placement of at least 11.5 mm-long implants (13 patients). Bone blocks and the windows at the maxillary sinuses were covered with rigid resorbable barriers. Grafts were left to heal for 4 months before placing implants which were submerged. After 4 months, provisional reinforced acrylic prostheses or bar retained overdentures were delivered. Provisional prostheses were replaced, after 4 months, by definitive screw-retained metal-resin cross-arch restorations. Outcome measures were prosthesis and implant failures, any complications, peri-implant marginal bone level changes and patient satisfaction. Patients were followed up to 1 year after loading.
All patients were rehabilitated with implant-supported prostheses but two patients dropped out from the augmented group. One bilateral sinus lift procedure failed for infection, although short implants could be placed. One implant failed in the augmented group versus two short implants in two patients (Fishers exact test P = 1.00; difference in proportions = 0.06; 95% CI -0.28 to 0.17). All failures occurred before loading. Significantly more complications occurred in augmented patients: eight complications occurred in 5 augmented patients (all of them complained of pain 1 month after bone harvesting from the iliac crest) versus no complications in the short implant (Fisher's exact test P = 0.013; difference in proportions = 0.38; 95% CI 0.11 to 0.65). Both groups presented a significant peri-implant marginal bone loss at 1 year after loading (P < 0.0001); -1.05 (0.20) mm for short implants and -1.01 (0.16) mm for the augmented group, respectively, with no statistically significant differences between the two groups (mean difference -0.04 mm; 95% CI -0.22 to 0.14; P = 0.59). All patients were fully satisfied with the treatment and would have it again.
This pilot study suggests that short implants may be a suitable, cheaper and faster alternative to longer implants placed in bone augmented with autogenous bone for rehabilitating edentulous atrophic maxillae, however, these preliminary results need to be confirmed by larger trials with follow-ups of at least 5 years.
评估短(5.0至8.5毫米)牙种植体是否可作为长(至少11.5毫米长)种植体的合适替代方案,后者用于植入经自体骨增量的萎缩性上颌骨以支持牙修复体。
28例全口无牙的萎缩性上颌骨患者,通过计算机断层扫描(CT)测量,其剩余牙槽嵴骨高度为5至9毫米且至少5毫米厚,随机分为两组,一组接受4至8枚短(5.0至8.5毫米)种植体(15例患者),另一组接受取自髂嵴的自体骨以植入至少11.5毫米长的种植体(13例患者)。上颌窦的骨块和开窗处用刚性可吸收屏障覆盖。移植骨愈合4个月后植入种植体,种植体为潜入式。4个月后,交付临时增强丙烯酸修复体或杆附着覆盖义齿。4个月后,临时修复体被确定性螺丝固位的金属 - 树脂跨牙弓修复体替代。观察指标为修复体和种植体失败情况、任何并发症、种植体周围边缘骨水平变化及患者满意度。患者在加载后随访1年。
所有患者均通过种植体支持的修复体进行了修复,但增强组有2例患者退出。尽管可以植入短种植体,但1例双侧上颌窦提升术因感染失败。增强组有1枚种植体失败,短种植体组有2例患者的2枚短种植体失败(Fisher精确检验P = 1.00;比例差异 = 0.06;95%可信区间 -0.28至0.17)。所有失败均发生在加载前。增强组患者出现的并发症明显更多:5例增强组患者出现8例并发症(所有患者在从髂嵴取骨后1个月均抱怨疼痛),而短种植体组无并发症(Fisher精确检验P = 0.013;比例差异 = 0.38;95%可信区间0.11至0.65)。两组在加载后1年时种植体周围边缘骨均有明显吸收(P < 0.0001);短种植体组为-1.05(0.20)毫米,增强组为-1.01(0.16)毫米,两组间无统计学显著差异(平均差异 -0.04毫米;95%可信区间 -0.22至0.14;P = 0.59)。所有患者对治疗完全满意,且愿意再次接受治疗。
这项初步研究表明,对于修复无牙的萎缩性上颌骨,短种植体可能是植入经自体骨增量的骨内长种植体的合适、更便宜且更快的替代方案,然而,这些初步结果需要通过至少5年随访的更大规模试验来证实。