Jagodnik Kathleen M, Blana Dimitra, van den Bogert Antonie J, Kirsch Robert F
Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; Fluid Physics and Transport Processes Branch, NASA Glenn Research Center, Cleveland, OH, United States; Center for Space Medicine, Baylor College of Medicine, Houston, TX, United States.
Institute for Science and Technology in Medicine, Keele University, UK.
J Biomech. 2015 Oct 15;48(13):3692-700. doi: 10.1016/j.jbiomech.2015.08.016. Epub 2015 Aug 29.
When Functional Electrical Stimulation (FES) is used to restore movement in subjects with spinal cord injury (SCI), muscle stimulation patterns should be selected to generate accurate and efficient movements. Ideally, the controller for such a neuroprosthesis will have the simplest architecture possible, to facilitate translation into a clinical setting. In this study, we used the simulated annealing algorithm to optimize two proportional-derivative (PD) feedback controller gain sets for a 3-dimensional arm model that includes musculoskeletal dynamics and has 5 degrees of freedom and 22 muscles, performing goal-oriented reaching movements. Controller gains were optimized by minimizing a weighted sum of position errors, orientation errors, and muscle activations. After optimization, gain performance was evaluated on the basis of accuracy and efficiency of reaching movements, along with three other benchmark gain sets not optimized for our system, on a large set of dynamic reaching movements for which the controllers had not been optimized, to test ability to generalize. Robustness in the presence of weakened muscles was also tested. The two optimized gain sets were found to have very similar performance to each other on all metrics, and to exhibit significantly better accuracy, compared with the three standard gain sets. All gain sets investigated used physiologically acceptable amounts of muscular activation. It was concluded that optimization can yield significant improvements in controller performance while still maintaining muscular efficiency, and that optimization should be considered as a strategy for future neuroprosthesis controller design.
当使用功能性电刺激(FES)来恢复脊髓损伤(SCI)患者的运动时,应选择肌肉刺激模式以产生准确且高效的运动。理想情况下,这种神经假体的控制器应具有尽可能简单的架构,以便于转化为临床应用。在本研究中,我们使用模拟退火算法为一个三维手臂模型优化了两组比例 - 微分(PD)反馈控制器增益,该模型包含肌肉骨骼动力学,具有5个自由度和22块肌肉,可执行目标导向的伸手动作。通过最小化位置误差、方向误差和肌肉激活的加权和来优化控制器增益。优化后,基于伸手动作的准确性和效率,以及其他三组未针对我们的系统进行优化的基准增益,在一大组控制器未针对其进行优化的动态伸手动作上评估增益性能,以测试其泛化能力。还测试了在肌肉力量减弱情况下的鲁棒性。结果发现,这两组优化后的增益在所有指标上彼此表现非常相似,并且与三组标准增益相比,具有显著更高的准确性。所有研究的增益组都使用了生理上可接受的肌肉激活量。得出的结论是,优化可以在保持肌肉效率的同时显著提高控制器性能,并且优化应被视为未来神经假体控制器设计的一种策略。