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获得性气管插管后气管食管瘘的外科治疗:27例患者。

Surgical management of acquired post-intubation tracheo-oesophageal fistulas: 27 patients.

作者信息

Marzelle J, Dartevelle P, Khalife J, Rojas-Miranda A, Chapelier A, Levasseur P

机构信息

Department of Thoracic and Vascular Surgery, Marie Lannelongue Hospital, Le Plessis Robinson, France.

出版信息

Eur J Cardiothorac Surg. 1989;3(6):499-502; discussion 502-3. doi: 10.1016/1010-7940(89)90108-5.

Abstract

From 1962 to 1987, 27 patients with tracheo-oesophageal fistulae (TOF) were treated at our institution. Mean age was 43 years. The indications for respiratory support were blunt chest trauma (11), neurological dysfunction (8), and acute pulmonary distress syndrome (8). TOF symptoms occurred 12-200 days (mean 43) after initiation of ventilatory support and was caused by tracheostomy tube cuff (17), intubation tube cuff (8), or injury at the site of tracheostomy (2). The size of the fistula ranged from 0.3 to 5 cm (mean 2 cm). Seventeen of the 27 patients were operated upon. A simple repair of the TOF was performed via a cervical approach in 10 patients; tracheal resection and reconstruction was done in 4 patients presenting with tracheal stenosis, while 2 patients with slight tracheal stenosis had a simple repair of the TOF without the need for further tracheal surgery. Three patients underwent primary oesophagostomy, followed later by colon interposition. Five patients died. Ten cases were not operated upon: the TOF closed spontaneously in 1 patient, 1 patient was lost to follow-up and 8 died. In our series, significant tracheal stenosis occurred in only 6 patients (22%), only 4 of whom had tracheal resection. Simple repair of TOF provides excellent results with a low mortality (10%) considering the poor condition of the patients, and should be considered the procedure of choice. Surgical oesophageal diversion (i.e. cervical oesophagostomy and suture of distal oesophagus) is usually unnecessary.

摘要

1962年至1987年期间,我院共治疗了27例气管食管瘘(TOF)患者。平均年龄为43岁。呼吸支持的适应证包括钝性胸部创伤(11例)、神经功能障碍(8例)和急性呼吸窘迫综合征(8例)。TOF症状在开始通气支持后12 - 200天(平均43天)出现,病因包括气管造口管套囊(17例)、气管插管套囊(8例)或气管造口部位损伤(2例)。瘘口大小为0.3至5厘米(平均2厘米)。27例患者中有17例接受了手术。10例患者通过颈部入路对TOF进行了简单修复;4例出现气管狭窄的患者进行了气管切除和重建,2例轻度气管狭窄患者对TOF进行了简单修复,无需进一步气管手术。3例患者接受了一期食管造口术,随后进行结肠间置术。5例患者死亡。10例患者未接受手术:1例患者的TOF自行闭合,1例患者失访,8例患者死亡。在我们的系列研究中,仅6例患者(22%)出现了明显的气管狭窄,其中只有4例接受了气管切除。考虑到患者的病情较差,TOF的简单修复效果良好,死亡率较低(10%),应被视为首选治疗方法。手术性食管改道(即颈部食管造口术和远端食管缝合术)通常没有必要。

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