Dayan Natalie, Spitzer Karen, Laskin Carl A
Department of Medicine, Division of General Internal Medicine, McGill University Health Centre, Montreal QC; LifeQuest Centre for Reproductive Medicine, University of Toronto, Toronto ON; Departments of Medicine and Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto ON.
LifeQuest Centre for Reproductive Medicine, University of Toronto, Toronto ON.
J Obstet Gynaecol Can. 2015 Jul;37(7):648-655. doi: 10.1016/S1701-2163(15)30204-8.
To describe current physician practice patterns in Canada with regard to performing in vitro fertilization in high-risk patients.
All medical directors of IVF clinics registered with the Canadian Fertility and Andrology Society (n=35) were invited to participate in an online survey between January and May 2014. We carried out descriptive analyses of participants' responses regarding implementation of local restrictive policies for access to IVF. Whether practice patterns differed in hospital versus community-based clinics was assessed using chi-square testing with significance set at alpha<0.05.
The response rate was 77.1%. More than one half of clinics (55.6%) were university-affiliated, and 29.6% were hospital-based. The majority of respondents (70.4%) used an upper age limit for permitting IVF (median 50 years, IQR 44 to 50), mostly because of lower pregnancy and live birth rates. Approximately one half of respondents limited treatment according to BMI (median upper permitted BMI 38 kg/m2, IQR 35 to 40 kg/m2) to minimize complications during pregnancy. Most respondents (77.8%) believed that routine pre-IVF medical assessment would be useful in their daily practice. There was a non-significant trend towards more restrictive policies in hospital-based clinics compared with community-based clinics.
Our findings confirm that Canadian reproductive medicine physicians are taking maternal health factors into consideration when assessing patients' suitability for IVF. Nevertheless, there is between-clinic variability in the parameters used to assess eligibility for treatment. In light of the changing maternal demographic, more research is needed on assisted reproductive technology and perinatal outcomes in women who are at risk for pregnancy complications.