文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

用超小超顺磁性氧化铁颗粒进行血管和斑块成像。

Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide.

作者信息

Alam Shirjel R, Stirrat Colin, Richards Jennifer, Mirsadraee Saeed, Semple Scott I K, Tse George, Henriksen Peter, Newby David E

机构信息

Centre for Cardiovascular Science, The University of Edinburgh, The Chancellor's Building, Little France Crescent, Edinburgh, EH16 5SA, UK.

Department of Cardiology, Royal Infirmary of Edinburgh, Edinburgh, EH16 5SA, UK.

出版信息

J Cardiovasc Magn Reson. 2015 Sep 18;17(1):83. doi: 10.1186/s12968-015-0183-4.

DOI:10.1186/s12968-015-0183-4
PMID:26381872
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4574723/
Abstract

Cardiovascular Magnetic Resonance (CMR) has become a primary tool for non-invasive assessment of cardiovascular anatomy, pathology and function. Existing contrast agents have been utilised for the identification of infarction, fibrosis, perfusion deficits and for angiography. Novel ultrasmall superparamagnetic particles of iron oxide (USPIO) contrast agents that are taken up by inflammatory cells can detect cellular inflammation non-invasively using CMR, potentially aiding the diagnosis of inflammatory medical conditions, guiding their treatment and giving insight into their pathophysiology. In this review we describe the utilization of USPIO as a novel contrast agent in vascular disease.

摘要

心血管磁共振成像（CMR）已成为无创评估心血管解剖结构、病理及功能的主要工具。现有的造影剂已被用于识别梗死、纤维化、灌注缺损以及血管造影。新型超小超顺磁性氧化铁（USPIO）造影剂可被炎症细胞摄取，利用CMR能无创检测细胞炎症，这可能有助于炎症性疾病的诊断、指导治疗并深入了解其病理生理学。在本综述中，我们描述了USPIO作为一种新型造影剂在血管疾病中的应用。

相似文献

[1]
Vascular and plaque imaging with ultrasmall superparamagnetic particles of iron oxide.

J Cardiovasc Magn Reson. 2015-9-18

[2]
Development of a magnetic resonance imaging protocol for the characterization of atherosclerotic plaque by using vascular cell adhesion molecule-1 and apoptosis-targeted ultrasmall superparamagnetic iron oxide derivatives.

Arterioscler Thromb Vasc Biol. 2012-4-19

[3]
Evaluation of ultrasmall superparamagnetic iron-oxide (USPIO) enhanced MRI with ferumoxytol to quantify arterial wall inflammation.

Atherosclerosis. 2017-6-8

[4]
Melatonin inhibits macrophage infiltration and promotes plaque stabilization by upregulating anti-inflammatory HGF/c-Met system in the atherosclerotic rabbit: USPIO-enhanced MRI assessment.

Vascul Pharmacol. 2020-2-15

[5]
Adipose tissue macrophages: MR tracking to monitor obesity-associated inflammation.

Radiology. 2012-4-20

[6]
Imaging pathobiology of carotid atherosclerosis with ultrasmall superparamagnetic particles of iron oxide: an update.

Curr Opin Cardiol. 2017-7

[7]
Ultra-small superparamagnetic iron oxide enhancement is associated with higher loss of brain tissue structure in clinically isolated syndrome.

Mult Scler. 2016-7

[8]
Identifying inflamed carotid plaques using in vivo USPIO-enhanced MR imaging to label plaque macrophages.

Arterioscler Thromb Vasc Biol. 2006-7

[9]
[Iron-oxide-enhanced MR imaging of inflammatory atherosclerotic lesions: overview of experimental and initial clinical results].

Rofo. 2003-4

[10]
The function and magnetic resonance imaging of immature dendritic cells under ultrasmall superparamagnetic iron oxide (USPIO)-labeling.

Biotechnol Lett. 2017-7

引用本文的文献

[1]
Radiomodulating Properties of Superparamagnetic Iron Oxide Nanoparticle (SPION) Agent Ferumoxytol on Human Monocytes: Implications for MRI-Guided Liver Radiotherapy.

Cancers (Basel). 2024-3-28

[2]
Diagnostics of atherosclerosis: Overview of the existing methods.

Front Cardiovasc Med. 2023-5-9

[3]
Longitudinal In Vivo Monitoring of Atheroprogression in Hypercholesterolemic Mice Using Photoacoustic Imaging.

Thromb Haemost. 2023-5

[4]
IL-6-targeted ultrasmall superparamagnetic iron oxide nanoparticles for optimized MRI detection of atherosclerotic vulnerable plaques in rabbits.

RSC Adv. 2020-4-17

[5]
Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis.

Cardiovasc Res. 2023-1-18

[6]
Myocardial inflammation and energetics by cardiac MRI: a review of emerging techniques.

BMC Med Imaging. 2021-11-8

[7]
Assessment of Albumin ECM Accumulation and Inflammation as Novel In Vivo Diagnostic Targets for Multi-Target MR Imaging.

Biology (Basel). 2021-9-27

[8]
Iron Oxide Nanoparticles in Regenerative Medicine and Tissue Engineering.

Nanomaterials (Basel). 2021-9-8

[9]
Different Approaches to Develop Nanosensors for Diagnosis of Diseases.

Adv Sci (Weinh). 2020-10-28

[10]
Ultra-high resolution, 3-dimensional magnetic resonance imaging of the atherosclerotic vessel wall at clinical 7T.

PLoS One. 2020

本文引用的文献

[1]
Vascular artifact mimicking thrombosis on MR imaging using ferumoxytol as a contrast agent in abdominal vascular assessment.

J Vasc Interv Radiol. 2014-6

[2]
Comparison of USPIO-enhanced MRI and Gd-DTPA enhancement during the subacute stage of focal cerebral ischemia in rats.

Acta Radiol. 2014-9

[3]
Atherosclerotic imaging using 4 types of superparamagnetic iron oxides: new possibilities for mannan-coated particles.

Eur J Radiol. 2013-9-1

[4]
Scavenger receptor-AI-targeted iron oxide nanoparticles for in vivo MRI detection of atherosclerotic lesions.

Arterioscler Thromb Vasc Biol. 2013-6-6

[5]
In vivo USPIO-enhanced MR signal characteristics of secondary degeneration in the ipsilateral substantia nigra after middle cerebral artery occlusion at 3T.

J Neuroradiol. 2013-2-18

[6]
Rapid binding of electrostatically stabilized iron oxide nanoparticles to THP-1 monocytic cells via interaction with glycosaminoglycans.

Basic Res Cardiol. 2013-1-12

[7]
Impact of surface coating and particle size on the uptake of small and ultrasmall superparamagnetic iron oxide nanoparticles by macrophages.

Int J Nanomedicine. 2012-10-10

[8]
High-resolution cerebral blood volume imaging in humans using the blood pool contrast agent ferumoxytol.

Magn Reson Med. 2013-9

[9]
Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience.

Circ Cardiovasc Imaging. 2012-8-8

[10]
Anti-inflammatory drug evaluation in ApoE-/- mice by ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging.

Invest Radiol. 2012-9

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索