Magnusson Ulf, Persson Sara
Division of Reproduction, Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Reprod Domest Anim. 2015 Sep;50 Suppl 3(Suppl 3):15-9. doi: 10.1111/rda.12563.
The objective of this review was to discuss whether endocrine disruption is a clinical concern in domestic animal reproduction. To that end, we firstly summarize the phenomenon of endocrine disruption, giving examples of the agents of concern and their effects on the mammalian reproductive system. Then there is a brief overview of the literature on endocrine disruptors and domestic animal reproduction. Finally, the clinical implications of endocrine disruptors on the reproductive system of farm animals as well as in dogs and cats are discussed. It is concluded that the evidence for clinical cases of endocrine disruption by chemical pollutants is weak, whereas for phytooestrogens, it is well established. However, there is concern that particular dogs and cats may be exposed to man-made endocrine disruptors.
本综述的目的是探讨内分泌干扰是否是家畜繁殖中的一个临床问题。为此,我们首先总结内分泌干扰现象,列举相关因素及其对哺乳动物生殖系统的影响。然后简要概述有关内分泌干扰物与家畜繁殖的文献。最后,讨论内分泌干扰物对农场动物以及犬猫生殖系统的临床影响。结论是,化学污染物导致内分泌干扰临床病例的证据不足,而植物雌激素导致内分泌干扰的证据确凿。然而,人们担心某些犬猫可能接触到人造内分泌干扰物。