Drózdz M, Tomala J, Jendryczko A, Banaś K
Ginekol Pol. 1989 Jun;60(6):301-5.
Lower concentrations of selenium and vitamin E were found in the serum of 50 women with malignant neoplasms of the genitals as compared with the concentrations in 55 healthy women family members of the patients living with them in common households. The degree of concentration decrease of these substances in the serum depended on the location of the tumour, and in cases of cervical neoplasms was 28% for selenium and 12% for vitamin E of the values in controls while in cases of ovarian neoplasms it was 34% and 37% respectively and in endometrial tumours it was 40% and 23% respectively. The third studied group comprised 36 healthy subjects not belonging to the families of the patients. The highest concentrations of selenium and vitamin E were found in the serum in the third group of women. The results suggest that various family factors not analysed in this study affect the concentrations of selenium and vitamin E in the serum of women with malignant neoplasms of genitals and in their family members.
与55名与患有生殖系统恶性肿瘤的女性共同生活在普通家庭中的健康女性家庭成员相比，50名患有生殖系统恶性肿瘤的女性血清中硒和维生素E的浓度较低。这些物质在血清中的浓度降低程度取决于肿瘤的位置，在宫颈癌病例中，硒的浓度为对照组的28%，维生素E为12%；而在卵巢癌病例中，分别为34%和37%；在子宫内膜癌病例中，分别为40%和23%。第三组研究对象为36名不属于患者家庭的健康受试者。在第三组女性血清中发现了最高浓度的硒和维生素E。结果表明，本研究未分析的各种家庭因素会影响患有生殖系统恶性肿瘤的女性及其家庭成员血清中硒和维生素E的浓度。
