Sundström H
Int J Vitam Nutr Res. 1985;55(4):433-8.
To explore the relationship between selenium deficiency in cancer and nutritional factors, we measured the serum concentrations of selenium in 1978-1983 in patients with gynaecological cancer (N = 277) and correlated these with the estimated daily intake of selenium, which varies in Finland depending on the proportion of selenium-rich imported grain. The selenium concentration increased significantly from 1978-1979 to 1982 in the series of all cancer patients (p less than 0.001) and separately in cases of cervical (p less than 0.001) and endometrial cancer (p less than 0.02), parallel to the increased daily intake of selenium. The serum level of selenium decreased in 1983, when the import of selenium-rich grain was reduced. Low serum selenium in cancer patients thus seems to be mainly dependent on dietary factors.
为了探究癌症患者体内硒缺乏与营养因素之间的关系，我们于1978 - 1983年测量了277例妇科癌症患者的血清硒浓度，并将其与估计的每日硒摄入量相关联，在芬兰，由于富含硒的进口谷物比例不同，每日硒摄入量也有所变化。在所有癌症患者系列中，从1978 - 1979年到1982年，硒浓度显著增加（p < 0.001），在宫颈癌（p < 0.001）和子宫内膜癌患者中分别显著增加（p < 0.02），这与每日硒摄入量的增加平行。1983年，当富含硒的谷物进口减少时，血清硒水平下降。因此，癌症患者血清硒水平低似乎主要取决于饮食因素。
