由第3天质量较差的胚胎发育而来的玻璃化囊胚移植后成功妊娠。
Successful pregnancy following the transfer of vitrified blastocyst which developed from poor quality embryos on day 3.
作者信息
Zhang Xiao-Jian, Yang Ye-Zhou, Min Li-Hua, Lv Qun, Bai Pin, Li Xiao-Jie, Liao Mei-Xu
机构信息
Department of Assisted Reproductive Medical Center, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Sichuan, China.
出版信息
Iran J Reprod Med. 2011 Summer;9(3):203-8.
BACKGROUND
The selection of pre-embryos for transferred is based on morphological appearance. But some poor quality cleaved embryos also can be cultured to the blastocyst stage and implanted.
OBJECTIVE
To assess the clinical pregnancy outcomes of blastocyst transfer which developed from poor quality embryos.
MATERIALS AND METHODS
A total of 109 cleaved embryos with poor quality were cultured to day 5/day 6 and 27 (24.8%) blastocysts were collected from the 15 cycles/patients undergoing conventional IVF. All the blastocysts were cooling with fast-freezing. Then the blastocysts were warmed for transfer.
RESULTS
All of 25 vitrified blastocysts (92.6%) survived after warming and were transferred to 15 patients. Five of the women became pregnant.
CONCLUSION
Our results suggest that vitrified human day 5/day 6 blastocyst transfer which develop from poor quality embryo at day 3 can contribute to increasing cumulative pregnancy rates in assisted reproduction.
背景
用于移植的胚胎前体选择基于形态外观。但一些质量较差的分裂期胚胎也能培养到囊胚阶段并植入。
目的
评估由质量差的胚胎发育而来的囊胚移植的临床妊娠结局。
材料与方法
总共109个质量差的分裂期胚胎培养至第5天/第6天，从15个接受常规体外受精的周期/患者中收集到27个（24.8%）囊胚。所有囊胚均采用快速冷冻法冷冻。然后将囊胚解冻用于移植。
结果
25个玻璃化囊胚解冻后全部存活（92.6%），并移植给15名患者。其中5名女性怀孕。
结论
我们的结果表明，由第3天质量差的胚胎发育而来的第5天/第6天玻璃化人囊胚移植有助于提高辅助生殖中的累积妊娠率。
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