Kocatürk Tolga, Erkan Erol, Eğrilmez Sait, Çakmak Harun, Dündar Sema O, Dayanir Volkan
Department of Ophthalmology, Faculty of Medicine, Adnan Menderes University, Aydın, Turkey.
Department of Ophthalmology, Faculty of Medicine, Ege University, Izmir, Turkey.
Open Ophthalmol J. 2015 Jul 31;9:121-5. doi: 10.2174/1874364101509010121. eCollection 2015.
To evaluate surgically induced astigmatism (SIA) after an intravitreal ranibizumab (IVR) injection.
Fifty eight eyes of 58 patients who underwent IVR injection due to age-related macular degeneration (wet form) or macular edema were included in this study. Patients' pre- and postoperative detailed ophthalmologic examinations were done and topographic keratometric values (K1, K2) were noted. Pre- and postoperative measurements were compared.
The mean preoperative astigmatism of 0.87 Diopters (D) was found to be 0.95 D, 0.75 D, 0.82 D and 0.78 D on the 1st day, 3rd day, 1st week and 1st month, respectively. After injection, absolute change in astigmatism was found to be 0.08 D, 0.12 D, 0.05 D and 0.09 D on the 1st day, 3rd day, 1st week and 1st month, respectively. The absolute change in astigmatism seemed to be insignificant in terms of refractive analysis, however; when we performed a vectorial analysis, which takes into account changes in the axis of astigmatism, the mean value of induced astigmatism were found to be 0.33±0.22 D, 0.32±0.29 D, 0.41±0.37 D, 0.46±0.32 D on the 1st day, 3rd day, 1st week and on 1st month, respectively.
Intravitreal injection is a minimally invasive ophthalmologic procedure, however; it may still cause statistically significant induced astigmatism when evaluated from a vectorial point of view.
评估玻璃体内注射雷珠单抗（IVR）后的手术诱导散光（SIA）。
本研究纳入了58例因年龄相关性黄斑变性（湿性）或黄斑水肿接受IVR注射的患者的58只眼。对患者进行术前和术后详细的眼科检查，并记录角膜地形图测量值（K1、K2）。比较术前和术后测量结果。
术前平均散光为0.87屈光度（D），在第1天、第3天、第1周和第1个月分别为0.95 D、0.75 D、0.82 D和0.78 D。注射后，散光的绝对变化在第1天、第3天、第1周和第1个月分别为0.08 D、0.12 D、0.05 D和0.09 D。然而，就屈光分析而言，散光的绝对变化似乎不显著；当我们进行考虑散光轴变化的矢量分析时，发现诱导散光的平均值在第1天、第3天、第1周和第1个月分别为0.33±0.22 D、0.32±0.29 D、0.41±0.37 D和0.46±0.32 D。
玻璃体内注射是一种微创眼科手术，然而；从矢量角度评估时，它仍可能导致具有统计学意义的诱导散光。
