一株携带肠致病性大肠杆菌基因的肠外致病性大肠杆菌导致的腹泻、菌血症和多器官功能障碍。
Diarrhea, bacteremia and multiorgan dysfunction due to an extraintestinal pathogenic Escherichia coli strain with enteropathogenic E. coli genes.
作者信息
Kessler Robert, Nisa Shahista, Hazen Tracy H, Horneman Amy, Amoroso Anthony, Rasko David A, Donnenberg Michael S
机构信息
Division of Infectious Diseases, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
The Institute for Genome Sciences and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
出版信息
Pathog Dis. 2015 Nov;73(8):ftv076. doi: 10.1093/femspd/ftv076. Epub 2015 Sep 26.
A 55-year-old man with well-controlled HIV had severe diarrhea for 3 weeks and developed multiorgan dysfunction and bacteremia due to Escherichia coli. The genome of the patient's isolate had features characteristic of extraintestinal pathogenic E. coli and genes distantly related to those defining enteropathogenic E. coli.
一名55岁的男性，其HIV病情控制良好，出现严重腹泻3周，并因大肠杆菌感染发展为多器官功能障碍和菌血症。患者分离株的基因组具有肠外致病性大肠杆菌的特征性特点，以及与定义肠致病性大肠杆菌的基因远缘相关的基因。
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