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在一系列体外测试条件下无约束型腰椎全椎间盘置换假体的磨损特性

Wear characteristics of an unconstrained lumbar total disc replacement under a range of in vitro test conditions.

作者信息

Hyde Philip J, Fisher John, Hall Richard M

机构信息

Institute of Medical and Biological Engineering, University of Leeds, Leeds, UK.

出版信息

J Biomed Mater Res B Appl Biomater. 2017 Jan;105(1):46-52. doi: 10.1002/jbm.b.33456. Epub 2015 Sep 28.

Abstract

The effect of kinematics, loading and centre of rotation on the wear of an unconstrained total disc replacement have been investigated using the ISO 18192-1 standard test as a baseline. Mean volumetric wear rate and surface morphological effects were reported. Changing the phasing of the flexions to create a low (but finite) amount of crossing path motion at the bearing surfaces resulted in a significant fall in wear volume. However, the rate of wear was still much larger than previously reported values under zero cross shear conditions. Reducing the load did not result in a significant change in wear rate. Moving the centre of rotation of the disc inferiorly did significantly increase wear rate. A phenomenon of debris re-attachment on the UHMWPE surface was observed and hypothesised to be due to a relatively harsh tribological operating regime in which lubricant replenishment and particle migration out of the bearing contact zone were limited. © 2015 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 105B: 46-52, 2017.

摘要

以ISO 18192-1标准测试为基线,研究了运动学、载荷和旋转中心对无约束全椎间盘置换假体磨损的影响。报告了平均体积磨损率和表面形态学效应。改变屈曲的相位以在轴承表面产生少量(但有限)的交叉路径运动,导致磨损量显著下降。然而,磨损率仍远高于先前报道的零交叉剪切条件下的值。降低载荷并未导致磨损率发生显著变化。将椎间盘的旋转中心向下移动确实显著增加了磨损率。观察到超高分子量聚乙烯(UHMWPE)表面存在碎屑重新附着的现象,并推测这是由于相对恶劣的摩擦学工作状态,其中润滑剂补充和颗粒从轴承接触区移出受到限制。©2015威利期刊公司。《生物医学材料研究杂志》B部分:应用生物材料,105B:46-52,2017年。

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