Kinzirskiĭ A S, Chernov V A, Shapovalova L M, Galochkina Z I, Mikhaĭlevskaia L L, Surovenkova N N
Vopr Onkol. 1989;35(8):961-7.
The effect of prospidin on Lewis lung carcinoma spreading under hyper- and hypocalcemia was studied. At early stages, increased extracellular calcium level was associated with inhibition of tumor dissemination to the lungs; however, later, colony growth was stimulated. Extracellular calcium level was shown to modulate the antitumor and antimetastatic effect of prospidin.
研究了脯氨idin在高钙血症和低钙血症条件下对Lewis肺癌扩散的影响。在早期，细胞外钙水平升高与肿瘤向肺部扩散的抑制有关；然而，在后期，集落生长受到刺激。结果表明，细胞外钙水平可调节脯氨idin的抗肿瘤和抗转移作用。
