[螺溴胺与前斯皮丁对免疫发生的影响]
[Effect of spirobramin and prospidin on immunogenesis].
作者信息
Gol'dberg E D, Mikhaĭlova T N, Zinger G V, Potapova G V, Chernov V A
出版信息
Farmakol Toksikol. 1984 Nov-Dec;47(6):56-9.
PMID:6542876
Abstract
The immunosuppressant effects of the antineoplastic piperazine drugs spirobramine and prospidin in respective doses of 500 and 600 mg/kg (1/2 of the LD50) were studied in experiments on cats. Spirobramine was shown to exert a more pronounced immunoinhibitory action on the primary and secondary immune response induced by sheep red blood cells.
摘要
在猫身上进行的实验研究了抗肿瘤哌嗪类药物螺溴胺和丙哌啶分别以500和600毫克/千克（半数致死量的1/2）剂量时的免疫抑制作用。结果表明，螺溴胺对绵羊红细胞诱导的初次和二次免疫反应具有更显著的免疫抑制作用。
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