Bittencourt Paulo Lisboa, Farias Alberto Queiroz, Terra Carlos
Paulo Lisboa Bittencourt, Unit of Gastroenterology and Hepatology, Portuguese Hospital, Salvador, BA 40140-901, Brazil.
World J Hepatol. 2015 Sep 28;7(21):2336-43. doi: 10.4254/wjh.v7.i21.2336.
Acute renal failure, now termed acute kidney injury (AKI), is frequently found in patients with cirrhosis. The occurrence of AKI, irrespective of the underlying cause, is associated with reduced in-hospital, 3-mo and 1-year survival. Hepatorenal syndrome is associated with the worst outcome among AKI patients with cirrhosis. Several definitions for AKI that have been proposed are outlined and evaluated in this paper. Among these, the International Club for Ascites-AKI criteria substantially strengthen the quality of early diagnosis and intervention according to underlying cause of AKI.
急性肾衰竭,现称为急性肾损伤(AKI),在肝硬化患者中很常见。无论潜在病因如何,AKI的发生都与住院期间、3个月和1年生存率降低有关。肝肾综合征在肝硬化AKI患者中预后最差。本文概述并评估了已提出的几种AKI定义。其中,国际腹水俱乐部-AKI标准根据AKI的潜在病因显著提高了早期诊断和干预的质量。