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Infectious Diseases Society of America and Gain-of-Function Experiments With Pathogens Having Pandemic Potential.

作者信息

Frank Gregory M, Adalja Amesh, Barbour Alan, Casadevall Arturo, Dormitzer Philip R, Duchin Jeff, Hayden Frederick G, Hirsch Martin S, Hynes Noreen A, Lipsitch Marc, Pavia Andrew T, Relman David A

机构信息

Infectious Diseases Society of America, Arlington.

UPMC Center for Health Security, University of Pittsburgh Medical Center, Pennsylvania.

出版信息

J Infect Dis. 2016 May 1;213(9):1359-61. doi: 10.1093/infdis/jiv474. Epub 2015 Sep 27.

DOI:10.1093/infdis/jiv474
PMID:26416656
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7313907/
Abstract
摘要

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本文引用的文献

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Gain-of-Function Research and the Relevance to Clinical Practice.功能获得性研究及其与临床实践的相关性。
J Infect Dis. 2016 May 1;213(9):1364-9. doi: 10.1093/infdis/jiv473. Epub 2015 Sep 27.
2
Is the debate and "pause" on experiments that alter pathogens with pandemic potential influencing future plans of graduate students and postdoctoral fellows?关于改变具有大流行潜力病原体的实验的辩论和“暂停”是否会影响研究生和博士后研究员的未来计划?
mBio. 2015 Jan 20;6(1):e02525-14. doi: 10.1128/mBio.02525-14.
3
Moratorium on research intended to create novel potential pandemic pathogens.暂停旨在创造新型潜在大流行病原体的研究。
mBio. 2014 Dec 12;5(6):e02366-14. doi: 10.1128/mBio.02366-14.
4
Gain-of-function experiments: time for a real debate.功能获得性实验:是时候进行一场真正的辩论了。
Nat Rev Microbiol. 2015 Jan;13(1):58-64. doi: 10.1038/nrmicro3405. Epub 2014 Dec 8.
5
An epistemological perspective on the value of gain-of-function experiments involving pathogens with pandemic potential.关于涉及具有大流行潜力病原体的功能获得性实验价值的认识论视角。
mBio. 2014 Sep 16;5(5):e01875-14. doi: 10.1128/mBio.01875-14.
6
Risks and benefits of gain-of-function experiments with pathogens of pandemic potential, such as influenza virus: a call for a science-based discussion.对具有大流行潜力的病原体(如流感病毒)进行功能获得性实验的风险与益处:呼吁开展基于科学的讨论。
mBio. 2014 Aug 1;5(4):e01730-14. doi: 10.1128/mBio.01730-14.
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The Irrationality of GOF Avian Influenza Virus Research.高致病性禽流感病毒研究的不合理性。
Front Public Health. 2014 Jul 16;2:77. doi: 10.3389/fpubh.2014.00077. eCollection 2014.
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MicroRNA-based strategy to mitigate the risk of gain-of-function influenza studies.基于 microRNA 的策略来降低功能获得性流感研究的风险。
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