Sengupta Swapnadeep, Mukherji Sudakshina, Sheet Jagabandhu, Mandal Anamitra, Swaika Sarbari
Department of Anaesthesiology and Critical Care, Medical College and Hospital, Kolkata, India.
Department of Anaesthesiology and Critical Care, IQ City Medical College, Durgapur, India.
Anesth Essays Res. 2015 May-Aug;9(2):208-12. doi: 10.4103/0259-1162.154541.
Caudal-epidural, the most commonly used regional analgesia technique, is virtually free of measurable hemodynamic effects, thus adding a new dimension to the evolving necessity of pediatric postoperative pain management. Though, bupivacaine is the most commonly used drug for this purpose, ropivacaine has emerged as a safer alternative, with the addition of opioids, like fentanyl, increasing the effective duration of analgesia. With this overview, our present study was designed to compare the postoperative analgesic efficacy of bupivacaine-fentanyl and ropivacaine-fentanyl combinations by caudal-epidural technique in pediatric infraumbilical surgeries.
Totally, 60 pediatric patients, of either sex, aged between 2 and 8 years, American Society of Anesthesiologists physical status I and II, undergoing elective infraumbilical surgeries were assigned into two groups, Group BF receiving bupivacaine 0.25%, 0.7 ml/kg and Group RF receiving ropivacaine 0.25%, 0.7 ml/kg with fentanyl 1 μg/kg added to each group. Assessment of pain was done using "Hannallah pain scale." Consumption of the total amount of rescue analgesic and time to requirement of the first dose, as also duration of motor blockade were noted. Perioperative hemodynamics and any adverse effects were monitored at regular intervals.
The RF Group experienced significantly longer duration of effective postoperative analgesia, with significantly shorter duration of motor blockade and lesser total analgesic requirement in comparison to the BF Group. Hemodynamically, patients in both the groups, were equally stable.
Ropivacaine, with an equipotent analgesic efficacy and a lesser duration of motor block, can be used as an alternative to bupivacaine for pediatric postoperative pain care through the caudal route.
骶管硬膜外阻滞是最常用的区域镇痛技术,几乎没有可测量的血流动力学影响,这为不断发展的小儿术后疼痛管理需求增添了新的维度。虽然布比卡因是最常用于此目的的药物,但罗哌卡因已成为一种更安全的替代品,加入阿片类药物(如芬太尼)可延长镇痛有效时间。基于此概述,我们目前的研究旨在比较布比卡因 - 芬太尼和罗哌卡因 - 芬太尼联合使用骶管硬膜外技术在小儿脐下手术中的术后镇痛效果。
总共60例年龄在2至8岁之间、美国麻醉医师协会身体状况分级为I级和II级、接受择期脐下手术的小儿患者被分为两组,BF组接受0.25%布比卡因,0.7 ml/kg,RF组接受0.25%罗哌卡因,0.7 ml/kg,每组均添加1 μg/kg芬太尼。使用“Hannallah疼痛量表”进行疼痛评估。记录急救镇痛药的总消耗量、首次给药时间以及运动阻滞持续时间。定期监测围手术期血流动力学和任何不良反应。
与BF组相比,RF组术后有效镇痛持续时间明显更长,运动阻滞持续时间明显更短,总镇痛需求量更少。在血流动力学方面,两组患者同样稳定。
罗哌卡因具有同等的镇痛效果且运动阻滞持续时间较短,可作为布比卡因的替代品,通过骶管途径用于小儿术后疼痛护理。