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腹腔镜手术治疗卵巢子宫内膜异位囊肿的手术时间可预测性如何?

How Predictable Is the Operative Time of Laparoscopic Surgery for Ovarian Endometrioma?

作者信息

Gambadauro Pietro, Campo Vincenzo, Campo Sebastiano

机构信息

Karolinska Institutet, LIME/NASP-C7, 17177 Stockholm, Sweden ; Department of Obstetrics and Gynaecology, Catholic University of the Sacred Heart, Largo A. Gemelli 8, 00168 Rome, Italy.

Department of Obstetrics and Gynaecology, Catholic University of the Sacred Heart, Largo A. Gemelli 8, 00168 Rome, Italy.

出版信息

Minim Invasive Surg. 2015;2015:702631. doi: 10.1155/2015/702631. Epub 2015 Aug 31.

Abstract

Endometriosis is a tricky albeit common disease whose management largely relies on laparoscopy. We have studied the operative times of laparoscopic endometrioma surgery in order to assess their predictability and possible predictors. One hundred forty-eight laparoscopies were included, with a median operative time of 70 minutes (mean 75.14; 95% CI: 70.03-80.24). Half of the cases had a duration within 15-20 minutes above or below the median (IQR: 55-93.75), but the whole dataset ranged from 20 to 180 minutes, and the standard deviation was relatively large (31.4). Surgical times were significantly related to technical (number and size of the cysts) and nontechnical factors (age, parity, dysmenorrhea, and family history). At multiple logistic regression, after adjusting for number and size of the cysts, surgical times below the first quartile were associated with older age (>30 years old: aOR: 3.590; 95% CI: 1.417-9.091) and parity (≥1 delivery: aOR: 3.409; 95% CI: 1.343-8.651). Longer times, above the third quartile, were instead predicted by a familial anamnesis of endometriosis (aOR: 3.639; 95% CI: 1.246-10.627). Our findings indicate highly variable surgical times, which are predicted by unexpected nontechnical factors. This is consistent with the complexity of endometriosis and its treatment. Productivity and efficiency in endometriosis surgery should focus on the quality of healthcare outcomes rather than on the time spent in the operating theatres.

摘要

子宫内膜异位症是一种棘手但常见的疾病,其治疗很大程度上依赖于腹腔镜检查。我们研究了腹腔镜下子宫内膜瘤手术的手术时间,以评估其可预测性及可能的预测因素。纳入了148例腹腔镜手术,中位手术时间为70分钟(平均75.14分钟;95%置信区间:70.03 - 80.24分钟)。一半的病例手术时长在中位数上下15 - 20分钟范围内(四分位间距:55 - 93.75分钟),但整个数据集范围为20至180分钟,且标准差相对较大(31.4)。手术时间与技术因素(囊肿数量和大小)及非技术因素(年龄、产次、痛经和家族史)显著相关。在多因素逻辑回归分析中,在调整囊肿数量和大小后,手术时间低于第一四分位数与年龄较大(>30岁:调整后比值比:3.590;95%置信区间:1.417 - 9.091)及产次(≥1次分娩:调整后比值比:3.409;95%置信区间:1.343 - 8.651)有关。而手术时间高于第三四分位数则由子宫内膜异位症家族史预测(调整后比值比:3.639;95%置信区间:1.246 - 10.627)。我们的研究结果表明手术时间高度可变,且由意想不到的非技术因素预测。这与子宫内膜异位症及其治疗的复杂性相一致。子宫内膜异位症手术的生产力和效率应关注医疗保健结果的质量,而非手术时间。

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