Michalczuk Marta, Urban Beata, Chrzanowska-Grenda Beata, Oziębło-Kupczyk Monika, Bakunowicz-Łazarczyk Alina
Department of Pediatric Ophthalmology and Strabismus, Medical University of Bialystok, Waszyngtona 17, 15-274 Bialystok, Poland.
Neural Plast. 2015;2015:754864. doi: 10.1155/2015/754864. Epub 2015 Aug 31.
The objective of our study was to examine a possible influence of gestational age, birth weight, and Apgar score on amplitudes and latencies of P100 wave in preterm born school-age children.
We examined the following group of school-age children: 28 with history of prematurity (mean age 10.56 ± 1.66 years) and 25 born at term (mean age 11.2 ± 1.94 years). The monocular PVEP was performed in all children.
The P100 wave amplitudes and latencies significantly differ between preterm born school-age children and those born at term. There was an essential positive linear correlation of the P100 wave amplitudes with birth weight, gestational age, and Apgar score. There were the negative linear correlations of P100 latencies in 15-minute stimulation from O1 and Oz electrode with Apgar score and O1 and O2 electrode with gestational age.
PVEP responses vary in preterm born children in comparison to term. Low birth weight, early gestational age, and poor baseline output seem to be the predicting factors for the developmental rate of a brain function in children with history of prematurity. Further investigations are necessary to determine perinatal factors that can affect the modified visual system function in preterm born children.
我们研究的目的是探讨胎龄、出生体重和阿氏评分对早产学龄儿童P100波振幅和潜伏期的可能影响。
我们检查了以下学龄儿童组：28名有早产史的儿童（平均年龄10.56±1.66岁）和25名足月出生的儿童（平均年龄11.2±1.94岁）。所有儿童均进行了单眼图形视觉诱发电位检查。
早产学龄儿童与足月出生儿童的P100波振幅和潜伏期存在显著差异。P100波振幅与出生体重、胎龄和阿氏评分之间存在显著的正线性相关性。在O1和Oz电极15分钟刺激下，P100潜伏期与阿氏评分呈负线性相关；在O1和O2电极刺激下，P100潜伏期与胎龄呈负线性相关。
与足月儿相比，早产儿的图形视觉诱发电位反应有所不同。低出生体重、早胎龄和较差的基线输出似乎是有早产史儿童脑功能发育速度的预测因素。有必要进一步研究以确定可能影响早产儿视觉系统功能改变的围产期因素。
