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本文引用的文献

1
Fiber-optic catheter-based polarization-sensitive OCT for radio-frequency ablation monitoring.基于光纤导管的偏振敏感光学相干断层扫描用于射频消融监测。
Opt Lett. 2014 Sep 1;39(17):5066-9. doi: 10.1364/OL.39.005066.
2
The influence of radiofrequency ablation patterns on length, histological and mechanical properties of tendons.射频消融模式对肌腱长度、组织学及力学性能的影响。
Muscles Ligaments Tendons J. 2012 Sep 10;2(2):85-90. Print 2012 Apr.
3
Effects of open-irrigated radiofrequency ablation catheter design on lesion formation and complications: in vitro comparison of 6 different devices.开放式灌注射频消融导管设计对损伤形成及并发症的影响：6种不同装置的体外比较
J Cardiovasc Electrophysiol. 2013 Oct;24(10):1157-62. doi: 10.1111/jce.12175. Epub 2013 May 29.
4
In vivo intracardiac optical coherence tomography imaging through percutaneous access: toward image-guided radio-frequency ablation.经皮心内光学相干断层成像术：实现影像引导的射频消融。
J Biomed Opt. 2011 Nov;16(11):110505. doi: 10.1117/1.3656966.
5
Advances in imaging for atrial fibrillation ablation.心房颤动消融成像技术的进展。
Radiol Res Pract. 2011;2011:714864. doi: 10.1155/2011/714864. Epub 2011 Feb 16.
6
Exposing gaps in linear radiofrequency lesions: form before function.揭示线性射频损伤中的间隙：功能之前的形态。
Circ Arrhythm Electrophysiol. 2011 Jun;4(3):257-9. doi: 10.1161/CIRCEP.111.963033.
7
Assessment of catheter tip contact force resulting in cardiac perforation in swine atria using force sensing technology.应用力感测技术评估在猪心房中导致心脏穿孔的导管尖端接触力。
Circ Arrhythm Electrophysiol. 2011 Apr;4(2):218-24. doi: 10.1161/CIRCEP.110.959429. Epub 2011 Jan 19.
8
Real-time lesion assessment using a novel combined ultrasound and radiofrequency ablation catheter.使用新型联合超声和射频消融导管实时评估病变。
Heart Rhythm. 2011 Feb;8(2):304-12. doi: 10.1016/j.hrthm.2010.10.039. Epub 2010 Oct 31.
9
Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).心房颤动管理指南：欧洲心脏病学会（ESC）心房颤动管理特别工作组
Eur Heart J. 2010 Oct;31(19):2369-429. doi: 10.1093/eurheartj/ehq278. Epub 2010 Aug 29.
10
Three-dimensional optical coherence tomography of Barrett's esophagus and buried glands beneath neosquamous epithelium following radiofrequency ablation.射频消融术后巴雷特食管及新鳞状上皮下埋藏腺体的三维光学相干断层扫描
Endoscopy. 2009 Sep;41(9):773-6. doi: 10.1055/s-0029-1215045. Epub 2009 Sep 10.

新型导管可实现同步射频消融和光学相干反射测量。

Novel catheter enabling simultaneous radiofrequency ablation and optical coherence reflectometry.

作者信息

Herranz D, Lloret Juan, Jiménez-Valero Santiago, Rubio-Guivernau J L, Margallo-Balbás Eduardo

机构信息

Medlumics S.L, Ronda de Poniente 6, 2A-B, 28760 Tres Cantos, Spain.

Medlumics S.L, Ronda de Poniente 6, 2A-B, 28760 Tres Cantos, Spain ; Servicio de Cardiología Intervencionista, Hospital Universitario La Paz, Madrid, Spain.

出版信息

Biomed Opt Express. 2015 Aug 7;6(9):3268-75. doi: 10.1364/BOE.6.003268. eCollection 2015 Sep 1.

DOI:10.1364/BOE.6.003268
PMID:26417499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4574655/
Abstract

A novel radiofrequency ablation catheter has been developed with integrated custom designed optics, enabling real-time monitoring of radiofrequency ablation procedures through polarization-sensitive optical coherence reflectometry. The optics allow for proper tissue illumination through a view-port machined in the catheter tip, thus providing lesion depth control over the RF ablation treatment. The system was verified in an in-vitro model of swine myocardium. Optical performance and thermal stability was confirmed after more than 25 procedures, without any damage to the optical assembly induced by thermal stress or material degradation. The use of this catheter in RF ablation treatments may make possible to assess lesion depth during therapy, thus translating into a reduction of potential complications on the procedure.

摘要

一种新型射频消融导管已被开发出来，它集成了定制设计的光学元件，能够通过偏振敏感光学相干反射测量法对射频消融手术进行实时监测。这些光学元件通过导管尖端加工的视口实现对组织的适当照明，从而在射频消融治疗中实现对病变深度的控制。该系统在猪心肌的体外模型中得到了验证。经过超过25次手术后，光学性能和热稳定性得到了确认，光学组件未因热应力或材料降解而受到任何损坏。在射频消融治疗中使用这种导管可能使在治疗过程中评估病变深度成为可能，从而减少手术中潜在并发症的发生。