Connolly Bronwen, O'Neill Brenda, Salisbury Lisa, McDowell Kathryn, Blackwood Bronagh
Lane Fox Clinical Respiratory Physiology Research Unit, Guy's and St. Thomas' NHS Foundation Trust, London, UK.
Centre of Human and Aerospace Physiological Sciences, King's College London, London, UK.
Syst Rev. 2015 Sep 29;4:130. doi: 10.1186/s13643-015-0119-y.
Patients admitted to the intensive care unit with critical illness often experience significant physical impairments, which typically persist for many years following resolution of the original illness. Physical rehabilitation interventions that enhance restoration of physical function have been evaluated across the continuum of recovery following critical illness including within the intensive care unit, following discharge to the ward and beyond hospital discharge. Multiple systematic reviews have been published appraising the expanding evidence investigating these physical rehabilitation interventions, although there appears to be variability in review methodology and quality. We aim to conduct an overview of existing systematic reviews of physical rehabilitation interventions for adult intensive care patients across the continuum of recovery.
METHODS/DESIGN: This protocol has been developed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocol (PRISMA-P) guidelines. We will search the Cochrane Systematic Review Database, Database of Abstracts of Reviews of Effectiveness, Cochrane Central Register of Controlled Trials, MEDLINE, Excerpta Medica Database and Cumulative Index to Nursing and Allied Health Literature databases. We will include systematic reviews of randomised controlled trials of adult patients, admitted to the intensive care unit and who have received physical rehabilitation interventions at any time point during their recovery. Data extraction will include systematic review aims and rationale, study types, populations, interventions, comparators, outcomes and quality appraisal method. Primary outcomes of interest will focus on findings reflecting recovery of physical function. Quality of reporting and methodological quality will be appraised using the PRISMA checklist and the Assessment of Multiple Systematic Reviews tool.
We anticipate the findings from this novel overview of systematic reviews will contribute to the synthesis and interpretation of existing evidence regarding physical rehabilitation interventions and physical recovery in post-critical illness patients across the continuum of recovery.
PROSPERO CRD42015001068.
入住重症监护病房的危重病患者常出现严重的身体功能障碍，这种障碍在原发病治愈后通常会持续多年。增强身体功能恢复的物理康复干预措施已在危重病康复的整个过程中得到评估，包括在重症监护病房内、出院至病房后以及出院后。尽管综述方法和质量似乎存在差异，但已发表了多项系统评价，对这些物理康复干预措施的不断增加的证据进行了评估。我们旨在对成年重症监护患者在整个康复过程中进行的物理康复干预措施的现有系统评价进行概述。
方法/设计：本方案是根据系统评价和Meta分析方案的首选报告项目（PRISMA-P）指南制定的。我们将检索Cochrane系统评价数据库、有效性评价文摘数据库、Cochrane对照试验中心注册库、MEDLINE、医学文摘数据库和护理及相关健康文献累积索引数据库。我们将纳入对成年患者随机对照试验的系统评价，这些患者入住重症监护病房，并在康复过程中的任何时间点接受了物理康复干预。数据提取将包括系统评价的目的和基本原理、研究类型、人群、干预措施、对照、结局和质量评估方法。感兴趣的主要结局将集中在反映身体功能恢复的结果上。报告质量和方法学质量将使用PRISMA清单和多重系统评价评估工具进行评估。
我们预计，这项对系统评价的全新概述的结果将有助于综合和解释关于危重病后患者在整个康复过程中进行物理康复干预和身体恢复的现有证据。
PROSPERO CRD42015001068。
