Hsu Jui-Feng, Chang Hsu-Liang, Tsai Ming-Ju, Tsai Ying-Ming, Lee Yen-Lung, Chen Pei-Huan, Fan Wen-Chieh, Su Yu-Chung, Yang Chih-Jen
Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, No. 68 Chunghwa 3rd Road, Cianjin District, 80145, Kaohsiung City, Taiwan.
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan.
World J Surg Oncol. 2015 Sep 30;13:288. doi: 10.1186/s12957-015-0707-2.
Implantable venous access port (IVAP)-related blood stream infections (BSIs) are one of the most common complications of implantable venous ports. The risk factors and pathogens for IVAP-related BSIs are still controversial.
We retrospectively reviewed all patients who received IVAPs at a Hospital in Taiwan from January 1, 2011 to June 31, 2014. Two types of venous port, BardPort® 6.6 fr (Bard port) and Autosuture Chemosite® 7.5 fr (TYCO port) were used. All patients with clinically proven venous port-related BSIs were enrolled.
A total of 552 patients were enrolled. There were 34 episodes of IVAP-related BSIs during the study period for a total incidence of 0.177 events/1000 catheter days. Port type (TYCO vs. Bard, HR = 7.105 (95% confidence interval (CI), 1.688-29.904), p = 0.0075), age > 65 years (HR = 2.320 (95 % CI, 1.179-4.564), p = 0.0148), and lung cancer (HR = 5.807 (95% CI, 2.946-11.447), p < 0.001) were risk factors for port infections. We also found that no local sign of infection was significantly associated with the growth of gram-negative bacilli (p = 0.031).
TYCO venous ports, age > 65 years, and lung cancer were all significant risk factors for IVAP-related BSIs, and no sign of infection was significantly associated with the growth of gram-negative bacilli.
植入式静脉输液港（IVAP）相关血流感染（BSIs）是植入式静脉输液港最常见的并发症之一。IVAP相关BSIs的危险因素和病原体仍存在争议。
我们回顾性分析了2011年1月1日至2014年6月31日在台湾一家医院接受IVAP的所有患者。使用了两种类型的静脉输液港，BardPort® 6.6 fr（巴德输液港）和Autosuture Chemosite® 7.5 fr（泰科输液港）。纳入所有临床确诊的静脉输液港相关BSIs患者。
共纳入552例患者。研究期间发生34例IVAP相关BSIs，总发生率为0.177事件/1000导管日。输液港类型（泰科与巴德，风险比[HR]=7.105（95%置信区间[CI]，1.688 - 29.904），p = 0.0075）、年龄>65岁（HR = 2.320（95% CI，1.179 - 4.564），p = 0.0148）和肺癌（HR = 5.807（95% CI，2.946 - 11.447），p < 0.001）是输液港感染的危险因素。我们还发现没有局部感染迹象与革兰氏阴性杆菌生长显著相关（p = 0.031）。
泰科静脉输液港、年龄>65岁和肺癌都是IVAP相关BSIs的重要危险因素，且没有感染迹象与革兰氏阴性杆菌生长显著相关。
