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巴西里约热内卢州通过病媒传播的急性恰加斯病的首次报告。

FIRST REPORT OF ACUTE CHAGAS DISEASE BY VECTOR TRANSMISSION IN RIO DE JANEIRO STATE, BRAZIL.

作者信息

Sangenis Luiz Henrique Conde, De Sousa Andréa Silvestre, Sperandio Da Silva Gilberto Marcelo, Xavier Sérgio Salles, Machado Carolina Romero Cardoso, Brasil Patrícia, De Castro Liane, Da Silva Sidnei, Georg Ingebourg, Saraiva Roberto Magalhães, do Brasil Pedro Emmanuel Alvarenga Americano, Hasslocher-Moreno Alejandro Marcel

机构信息

Instituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, BR.

Intituto Nacional de Infectologia Evandro Chagas, Fundação Oswaldo Cruz, Rio de Janeiro, RJ, BR.

出版信息

Rev Inst Med Trop Sao Paulo. 2015 Jul-Aug;57(4):361-4. doi: 10.1590/S0036-46652015000400017.

DOI:10.1590/S0036-46652015000400017
PMID:26422165
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4616926/
Abstract

Chagas disease (CD) is an endemic anthropozoonosis from Latin America of which the main means of transmission is the contact of skin lesions or mucosa with the feces of triatomine bugs infected by Trypanosoma cruzi. In this article, we describe the first acute CD case acquired by vector transmission in the Rio de Janeiro State and confirmed by parasitological, serological and PCR tests. The patient presented acute cardiomyopathy and pericardial effusion without cardiac tamponade. Together with fever and malaise, a 3 cm wide erythematous, non-pruritic, papule compatible with a "chagoma" was found on his left wrist. This case report draws attention to the possible transmission of CD by non-domiciled native vectors in non-endemic areas. Therefore, acute CD should be included in the diagnostic workout of febrile diseases and acute myopericarditis in Rio de Janeiro.

摘要

恰加斯病(CD)是一种源自拉丁美洲的地方性人畜共患病,其主要传播途径是皮肤损伤或黏膜与感染克氏锥虫的锥蝽粪便接触。在本文中,我们描述了里约热内卢州首例经媒介传播获得并经寄生虫学、血清学和PCR检测确诊的急性恰加斯病病例。该患者表现为急性心肌病和心包积液,但无心脏压塞。除发热和不适外,在其左手腕发现一个3厘米宽的红斑、无瘙痒的丘疹,符合“恰加斯肿”。本病例报告提醒人们注意非流行地区非定居本地媒介可能传播恰加斯病。因此,里约热内卢的发热性疾病和急性心肌心包炎的诊断检查应包括急性恰加斯病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7a/4616926/af142bc7befe/0036-4665-rimtsp-57-04-00361-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7a/4616926/37c5b746ae55/0036-4665-rimtsp-57-04-00361-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7a/4616926/a39cc4d38a24/0036-4665-rimtsp-57-04-00361-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7a/4616926/af142bc7befe/0036-4665-rimtsp-57-04-00361-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7a/4616926/37c5b746ae55/0036-4665-rimtsp-57-04-00361-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7a/4616926/a39cc4d38a24/0036-4665-rimtsp-57-04-00361-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e7a/4616926/af142bc7befe/0036-4665-rimtsp-57-04-00361-gf03.jpg

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