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巴西版儿童哮喘控制测试(c-ACT)的验证

Validation of the Brazilian version of the childhood asthma control test (c-ACT).

作者信息

Oliveira Suelen G, Sarria Edgar E, Roncada Cristian, Stein Renato T, Pitrez Paulo M, Mattiello Rita

机构信息

Centro Infant, Biomedical Research Institute, Pontifícia Universidade Católica do Rio Grande (PUCRS), Porto Alegre, Brazil.

Department of Biology and Pharmacy, School of Medicine, Universidade de Santa Cruz do Sul (UNISC), Santa Cruz do Sul, Brazil.

出版信息

Pediatr Pulmonol. 2016 Apr;51(4):358-63. doi: 10.1002/ppul.23318. Epub 2015 Sep 30.

DOI:10.1002/ppul.23318
PMID:26422330
Abstract

BACKGROUND

Children's perception of their symptoms has proved reliable and relevant to disease management and should be considered when assessing their asthma control. The aim of the study is to validate the Brazilian Portuguese version of the Childhood Asthma Control Test (c-ACT) in children aged 4-11 years.

METHODS

This is a cross-sectional study in children diagnosed with asthma undergoing treatment in a pediatric pulmonology outpatient clinic in Porto Alegre, Brazil. The translation and linguistic adaptation of the instrument were performed in accordance with international recommendations for questionnaire validation.

RESULTS

A total of 105 participants were included, aged 4-11 years.

VALIDITY

all correlations between the total score and items on the questionnaire were significant and obtained values of r ≥ 0.3, and c-ACT means showed statistically significant differences between the GINA categories (P < 0.01). The controlled asthma group showed significantly higher c-ACT scores than those of uncontrolled asthma group (controlled 22.0 ± 2.9 vs. uncontrolled 16.3 ± 5.3 P < 0.01); and partially controlled asthma group showed significantly higher c-ACT scores than those of uncontrolled asthma group (partially controlled 20.0 ± 4.0 vs. uncontrolled 16.3 ± 5.3 P = 0.03). Correlations between the c-ACT total score and spirometry and nitric oxide were poor (r = 0.020; P = 0.866 and r = 0.035; P = 0.753, respectively). Reliability: the α-C coefficient for the c-ACT total score was 0.677 (95%CI 0.573-0763). Sensitivity to change had an effect size of 0.8 and an intraclass correlation coefficient of 0.598. No floor or ceiling effects were observed.

CONCLUSION

The Brazilian version of the Childhood Asthma Control Test proved to be valid and reliable in children aged 4-11 years.

摘要

背景

儿童对自身症状的感知已被证明是可靠的,且与疾病管理相关,在评估儿童哮喘控制情况时应予以考虑。本研究的目的是验证巴西葡萄牙语版儿童哮喘控制测试(c-ACT)在4至11岁儿童中的有效性。

方法

这是一项横断面研究,研究对象为在巴西阿雷格里港一家儿科肺病门诊接受治疗的哮喘患儿。该工具的翻译和语言改编是根据问卷验证的国际建议进行的。

结果

共纳入105名4至11岁的参与者。

有效性

问卷总分与各项目之间的所有相关性均显著,r值≥0.3,且c-ACT均值在全球哮喘防治创议(GINA)各分类之间显示出统计学显著差异(P<0.01)。哮喘控制组的c-ACT得分显著高于未控制哮喘组(控制组22.0±2.9 vs.未控制组16.3±5.3,P<0.01);部分控制哮喘组的c-ACT得分显著高于未控制哮喘组(部分控制组20.0±4.0 vs.未控制组16.3±5.3,P=0.03)。c-ACT总分与肺功能测定和一氧化氮之间的相关性较差(r=0.020;P=0.866和r=0.035;P=0.753)。可靠性:c-ACT总分的α-C系数为0.677(95%置信区间0.573-0.763)。变化敏感性的效应大小为0.8,组内相关系数为0.598。未观察到地板效应或天花板效应。

结论

巴西版儿童哮喘控制测试在4至11岁儿童中被证明是有效且可靠的。

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