Amorim Cláudio Luiz Castro Gomes de, Furlanetto Karina Couto, Corsi Thaila, Pitta Fabio
. Programa de Pós-Graduação em Ciências da Saúde, Universidade Estadual de Londrina, Londrina (PR) Brasil.
. Laboratório de Pesquisa em Fisioterapia Pulmonar, Departamento de Fisioterapia, Universidade Estadual de Londrina, Londrina (PR) Brasil.
J Bras Pneumol. 2025 Jun 13;51(2):e20240407. doi: 10.36416/1806-3756/e20240407. eCollection 2025.
To investigate the level of agreement between the GINA questionnaire and the Asthma Control Test (ACT) in children and adolescents with asthma, as well as to compare the clinical, laboratory, and spirometric characteristics of patients with controlled and uncontrolled asthma as assessed by the two questionnaires.
Children and adolescents with asthma had their level of asthma control cross-sectionally assessed by the GINA questionnaire and the ACT, the Childhood ACT (C-ACT) being used for the children in the sample. The participating patients also underwent spirometry, clinical assessment (for passive smoking, asthma severity, medication use, and type of inhaler device used), and laboratory measurements of vitamin D levels, blood eosinophils, and total IgE.
A total of 76 patients were assessed. Of those, 62% were male, and the mean age was 10 [9-12] years. In addition, 42% and 20% were classified as having uncontrolled asthma by the GINA questionnaire and the C-ACT/ACT, respectively. There was moderate agreement between the two questionnaires regarding identification of controlled and uncontrolled asthma (k = 0.505; p < 0,0001). The patients classified as having uncontrolled asthma by the GINA questionnaire had worse results in terms of daily inhaled corticosteroid dose, asthma severity, passive smoking, and spirometric parameters (FVC, FEV1, and FEF25-75%). However, there was no significant difference between patients classified as having controlled or uncontrolled asthma by the C-ACT/ACT.
In children and adolescents with asthma, the level of agreement between the GINA questionnaire and the C-ACT/ACT appears to be moderate. The GINA questionnaire appears to have a stronger association with functional parameters, indicating better clinical assessment with less underreporting of uncontrolled asthma.
调查全球哮喘防治创议（GINA）问卷与哮喘控制测试（ACT）在儿童和青少年哮喘患者中的一致性水平，并比较通过这两种问卷评估的哮喘控制良好和未控制患者的临床、实验室及肺功能特征。
采用GINA问卷和ACT对儿童和青少年哮喘患者的哮喘控制水平进行横断面评估，样本中的儿童使用儿童版ACT（C-ACT）。参与研究的患者还接受了肺功能测定、临床评估（包括被动吸烟情况、哮喘严重程度、药物使用及吸入装置类型）以及维生素D水平、血液嗜酸性粒细胞和总IgE的实验室检测。
共评估了76例患者。其中，62%为男性，平均年龄为10[9 - 12]岁。此外，分别有42%和20%的患者被GINA问卷和C-ACT/ACT判定为哮喘未控制。在哮喘控制和未控制的识别方面，两种问卷之间存在中度一致性（k = 0.505；p < 0.0001）。被GINA问卷判定为哮喘未控制的患者在每日吸入糖皮质激素剂量、哮喘严重程度、被动吸烟及肺功能参数（FVC、FEV1和FEF25 - 75%）方面结果更差。然而，被C-ACT/ACT判定为哮喘控制或未控制的患者之间无显著差异。
在儿童和青少年哮喘患者中，GINA问卷与C-ACT/ACT之间的一致性水平似乎为中度。GINA问卷似乎与功能参数有更强的关联，表明其临床评估更好，对未控制哮喘的漏报更少。
