Tan Aaron, Chawla Reema, G Natasha, Mahdibeiraghdar Sara, Jeyaraj Rebecca, Rajadas Jayakumar, Hamblin Michael R, Seifalian Alexander M
UCL Medical School, University College London (UCL), London, England, UK; Biomaterials & Advanced Drug Delivery Laboratory (BioADD), Stanford University School of Medicine, Stanford University, Stanford, CA, USA.
Department of Plastic & Reconstructive Surgery, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, England, UK.
J Plast Reconstr Aesthet Surg. 2016 Jan;69(1):1-13. doi: 10.1016/j.bjps.2015.08.028. Epub 2015 Sep 6.
The rapid ascent of nanotechnology and regenerative therapeutics as applied to medicine and surgery has seen an exponential rise in the scale of research generated in this field. This is evidenced not only by the sheer volume of papers dedicated to nanotechnology but also in a large number of new journals dedicated to nanotechnology and regenerative therapeutics specifically to medicine and surgery. Aspects of nanotechnology that have already brought benefits to these areas include advanced drug delivery platforms, molecular imaging and materials engineering for surgical implants. Particular areas of interest include nerve regeneration, burns and wound care, artificial skin with nanoelectronic sensors and head and neck surgery. This study presents a review of nanotechnology and regenerative therapeutics, with focus on its applications and implications in plastic surgery.
纳米技术和再生疗法在医学和外科领域的迅速崛起，使得该领域产生的研究规模呈指数级增长。这不仅体现在专门论述纳米技术的论文数量之多，还体现在大量专门针对医学和外科领域的纳米技术及再生疗法的新期刊上。纳米技术已给这些领域带来益处的方面包括先进的药物递送平台、分子成像以及用于外科植入物的材料工程。特别感兴趣的领域包括神经再生、烧伤与伤口护理、带有纳米电子传感器的人造皮肤以及头颈外科手术。本研究对纳米技术和再生疗法进行了综述，重点关注其在整形手术中的应用及影响。
