Bläckberg Anna, Trell Kristina, Rasmussen Magnus
Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
BMC Infect Dis. 2015 Sep 30;15:402. doi: 10.1186/s12879-015-1134-2.
Erysipelas is a common and severe infection where the aetiology and optimal management is not well-studied. Here, we investigate the clinical features, bacteriological aetiology, and treatment of erysipelas.
Episodes of erysipelas in a seven-years period in our institution were studied retrospectively using a pre-specified protocol and is presented with descriptive and comparative statistics.
1142 episodes of erysipelas were identified in 981 patients. Patients had a median age of 61 years, 59 % were male, a majority had underlying diseases or predisposing conditions, and the leg was most often affected. Wound cultures were taken in 343 episodes and 56 grew group A streptococci (GAS), 53 grew group G streptococci (GGS), 11 grew group C streptococci (GCS), and 153 grew Staphylococcus aureus. Blood cultures were drawn in 49 % of episodes and 50 cultures were positive with GGS as the most common finding (21 cultures) followed by GAS in 13, group B streptococci in 5, S. aureus in 4, and GCS in 3 cultures. In 45 % of episodes, patients received antibiotics with activity against S. aureus.
GGS is the most common streptococcus isolated in erysipelas and the role of S. aureus in erysipelas remains elusive.
丹毒是一种常见且严重的感染性疾病，其病因及最佳治疗方法尚未得到充分研究。在此，我们对丹毒的临床特征、细菌学病因及治疗进行调查。
回顾性研究我们机构7年内的丹毒病例，采用预先设定的方案，并进行描述性和比较性统计分析。
在981例患者中确诊了1142例丹毒病例。患者的中位年龄为61岁，59%为男性，大多数患者有基础疾病或易感因素，最常受累的部位是腿部。在343例病例中进行了伤口培养，56例培养出A组链球菌（GAS），53例培养出G组链球菌（GGS），11例培养出C组链球菌（GCS），153例培养出金黄色葡萄球菌。49%的病例进行了血培养，50例培养结果呈阳性，其中最常见的是GGS（21例），其次是GAS（13例）、B组链球菌（5例）、金黄色葡萄球菌（4例）和GCS（3例）。45%的病例中，患者接受了针对金黄色葡萄球菌的抗生素治疗。
GGS是丹毒中最常见分离出的链球菌，金黄色葡萄球菌在丹毒中的作用仍不明确。
