German A J, Titcomb J M, Holden S L, Queau Y, Morris P J, Biourge V
Department of Obesity and Endocrinology, University of Liverpool, Leahurst Campus, Chester High Road, Neston, Wirral, CH64 7TE, UK.
The School of Veterinary Science, University of Liverpool, Leahurst Campus, Chester High Road, Neston, Wirral, CH64 7TE, UK.
J Vet Intern Med. 2015 Nov-Dec;29(6):1547-55. doi: 10.1111/jvim.13629. Epub 2015 Oct 1.
Most weight loss studies in obese dogs assess rate and percentage of weight loss in the first 2-3 months, rather than the likelihood of successfully reaching target weight.
To determine outcome of controlled weight loss programs for obese dogs, and to determine the factors associated with successful completion.
143 obese dogs undergoing a controlled weight loss program.
This was a cohort study of obese dogs attending a referral weight management clinic. Dogs were studied during their period of weight loss, and cases classified according to outcome as "completed" (reached target weight), "euthanized" (was euthanized before reaching target weight), or "stopped prematurely" (program stopped early for other reasons). Factors associated with successful completion were assessed using simple and multiple logistic regression.
87/143 dogs (61%) completed their weight loss program, 11 [8%] died or were euthanized, and the remaining 45 [32%] stopped prematurely. Reasons for dogs stopping prematurely included inability to contact owner, refusal to comply with weight management advice, or development of another illness. Successful weight loss was positively associated with a faster rate (P < .001), a longer duration (P < .001), and feeding a dried weight management diet (P = .010), but negatively associated with starting body fat (P < .001), and use of dirlotapide (P = .0046).
Just over half of all obese dogs on a controlled weight loss program reach their target weight. Future studies should better clarify reasons for success in individual cases, and also the role of factors such as activity and behavioral modification.
大多数针对肥胖犬的体重减轻研究评估的是前2至3个月内体重减轻的速率和百分比，而非成功达到目标体重的可能性。
确定肥胖犬控制体重计划的结果，并确定与成功完成计划相关的因素。
143只接受控制体重计划的肥胖犬。
这是一项对前往转诊体重管理诊所的肥胖犬进行的队列研究。在犬体重减轻期间对其进行研究，并根据结果将病例分类为“完成”（达到目标体重）、“实施安乐死”（在达到目标体重之前实施安乐死）或“过早停止”（因其他原因提前停止计划）。使用简单和多元逻辑回归评估与成功完成计划相关的因素。
143只犬中有87只（61%）完成了体重减轻计划，11只（8%）死亡或实施了安乐死，其余45只（32%）过早停止。犬过早停止的原因包括无法联系到主人、拒绝遵守体重管理建议或患上其他疾病。成功减重与更快的减重速率（P < .001）、更长的持续时间（P < .001）以及喂食干制体重管理日粮（P = .010）呈正相关，但与起始体脂（P < .001）和使用氯吡脲（P = .0046）呈负相关。
在接受控制体重计划的所有肥胖犬中，略超过一半的犬达到了目标体重。未来的研究应更好地阐明个别病例成功的原因，以及活动和行为改变等因素的作用。
