Philpott Hamish, Nandurkar Sanjay, Royce Simon G, Gibson Peter R
Monash University.
Eastern Health.
J Gastroenterol Hepatol. 2016 Mar;31(3):590-4. doi: 10.1111/jgh.13173.
Ultrathin unsedated transnasal gastroscopy (UTEG) has a number of advantages applicable to eosinophilic esophagitis (EoE) and has not been evaluated for this condition.
The aim of the study is to determine the feasibility of UTEG in patients with EoE and the acceptability of histological specimens obtained at biopsy.
All patients with a diagnosis of EoE presenting to the outpatients department of two hospitals (Box Hill Hospital and The Alfred Hospital, Melbourne Australia) were asked to participate in the study. UTEG was performed on consenting individuals. Feasibility was determined by the success of nasal intubaton, patient perception according to post procedural survey, and adequacy of esophageal biopsies was assessed.
Ninety-six consecutive patients with EoE were offered UTEG, and 24 agreed to participate in the study. Seventy-four UTEGs were performed over a period of 26 months (September 2012 to December 2014). Nineteen patients had repeat procedures. Successful nasal intubation occurred in 97% (72 of 74 procedures), and 21 of 24 (86%) described high satisfaction with the procedure and minimal discomfort, and would choose UTEG for future procedures. Mean duration was 5 min. Adverse events of epistaxis (three cases) and vomiting of liquid contents during the procedure (two cases) were recorded, cardiorespiratory parameters remaining normal in all patients. All completed procedures produced adequate histological samples.
In those who decide to undergo UTEG, it is a safe and well-tolerated procedure.
超薄非镇静经鼻胃镜检查（UTEG）具有多项适用于嗜酸性食管炎（EoE）的优势，且尚未针对该病症进行评估。
本研究旨在确定UTEG在EoE患者中的可行性以及活检获取的组织学标本的可接受性。
邀请两所医院（澳大利亚墨尔本的博克斯希尔医院和阿尔弗雷德医院）门诊诊断为EoE的所有患者参与研究。对同意参与的个体进行UTEG检查。通过鼻插管的成功率、术后调查患者的感受来确定可行性，并评估食管活检的充分性。
连续96例EoE患者被提供UTEG检查，24例同意参与研究。在26个月（2012年9月至2014年12月）期间进行了74次UTEG检查。19例患者接受了重复检查。97%（74次检查中的72次）成功进行了鼻插管，24例中的21例（86%）对该检查表示高度满意且不适最小，并表示未来会选择UTEG检查。平均时长为5分钟。记录到鼻出血不良事件3例，检查过程中液体内容物呕吐不良事件2例，所有患者的心肺参数均保持正常。所有完成的检查均获得了足够的组织学样本。
对于决定接受UTEG检查的患者，该检查是一种安全且耐受性良好的操作。
