Spaide Richard F
The Vitreous, Retina, Macula Consultants of New York, New York, New York.
Retina. 2015 Nov;35(11):2181-7. doi: 10.1097/IAE.0000000000000764.
To demonstrate combined and integrated volume rendering of the retinal vasculature and selected structural abnormalities information derived from optical coherence tomography.
The eyes were scanned using optical coherence tomography using split-spectrum amplitude-decorrelation techniques to derive flow information. Various sublayers could be color coded as needed. The corresponding structural optical coherence tomography information was segmented for salient anatomic structures of interest, such as areas of edema fluid or intraretinal lipid deposits. The angiographic and structural data were integrated on a plane-by-plane basis and used to create volume-rendered images. The combined volume-rendered angiographic and structural optical coherence tomography data could be rotated about three different axes for evaluation.
Representative images from the eyes with diabetic macular edema, Type 1 macular telangiectasis, choroidal neovascularization, and retinal veno-occlusive disease are shown. The interrelationships between areas of cystoid fluid accumulation or intraretinal lipid accumulation could be visualized.
Although structural and angiographic findings are typically shown in isolation, they can be integrated into a merged data set that is amenable to volume rendering. Using this new technique will allow investigation into the interrelationships between vascular and structural abnormalities of the retina and choroid.
展示视网膜血管系统的联合及整合体层成像,以及源自光学相干断层扫描的选定结构异常信息。
使用光学相干断层扫描,采用分谱幅度去相关技术对眼睛进行扫描以获取血流信息。可根据需要对各个子层进行颜色编码。针对感兴趣的显著解剖结构,如水肿液区域或视网膜内脂质沉积区域,对相应的结构光学相干断层扫描信息进行分割。血管造影和结构数据逐平面整合,并用于创建体层成像图像。联合的体层成像血管造影和结构光学相干断层扫描数据可围绕三个不同轴旋转以进行评估。
展示了患有糖尿病性黄斑水肿、1型黄斑毛细血管扩张症、脉络膜新生血管和视网膜静脉阻塞性疾病的眼睛的代表性图像。可以可视化囊样液体积聚区域或视网膜内脂质积聚区域之间的相互关系。
尽管结构和血管造影结果通常单独显示,但它们可以整合到一个适合体层成像的合并数据集中。使用这项新技术将有助于研究视网膜和脉络膜血管与结构异常之间的相互关系。