MEMORIAL SLOAN KETTERING CANCER CENTER.
Blood. 2015 Oct 1;126(14):1641-2. doi: 10.1182/blood-2015-08-661504.
In this issue of Blood, Weber and colleagues demonstrate that in the first 10 days following allogeneic hematopoietic transplantation, urinary 3-indoxyl sulfate is a biomarker of intestinal microbiota health and predicts reduced intestinal graft-versus-host disease (GVHD) and treatment-related mortality, as well as improved overall survival.
在本期《Blood》中,Weber 及其同事表明,在异基因造血干细胞移植后的头 10 天内,尿液中的 3-吲哚硫酸酯是肠道微生物组健康的生物标志物,可预测减少肠道移植物抗宿主病(GVHD)和治疗相关死亡率,并改善总生存率。