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一名有症状的韩国威尔逊病患者成功妊娠结局。

Successful pregnancy outcome in a Korean patient with symptomatic Wilson's disease.

作者信息

Lee Hyun Joo, Seong Won Joon, Hong Seong Yeon, Bae Jin Young

机构信息

Department of Obstetrics and Gynecology, Catholic University of Daegu School of Medicine, Daegu, Korea.

Department of Obstetrics and Gynecology, Kyungpook National University Hospital, Daegu, Korea.

出版信息

Obstet Gynecol Sci. 2015 Sep;58(5):409-13. doi: 10.5468/ogs.2015.58.5.409. Epub 2015 Sep 22.

Abstract

Wilson's disease is an inherited disease of copper metabolism leading to the toxic accumulation of copper, primarily in the liver and brain. Although the literature shows successful outcomes after proper treatment, pregnant patients with Wilson's disease still need close monitoring and management. Here, we report the case of a successful pregnancy in a Korean woman with Wilson's disease. A 33-year-old primigravid patient with Wilson's disease visited our antenatal clinic. Of her own volition, she had stopped her medication 2 years earlier. Oral zinc oxide therapy was started, and she was closely monitored throughout her pregnancy. She delivered a healthy female infant weighing 3.13 kg through a cesarean section. After delivery, the clinical course of both the mother and the baby were uneventful. We review crucial points in the treatment and the management dilemmas raised by the patient.

摘要

威尔逊病是一种铜代谢的遗传性疾病,会导致铜的毒性蓄积,主要在肝脏和大脑中。尽管文献表明经过适当治疗后会有成功的结果,但患有威尔逊病的孕妇仍需要密切监测和管理。在此,我们报告一例患有威尔逊病的韩国女性成功怀孕的病例。一名33岁患有威尔逊病的初产妇到我们的产前诊所就诊。她出于自己的意愿,在两年前就停止了用药。开始口服氧化锌治疗,并在整个孕期对她进行密切监测。她通过剖宫产分娩了一名体重3.13千克的健康女婴。产后,母亲和婴儿的临床过程均顺利。我们回顾了治疗中的关键点以及患者引发的管理难题。

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A Case of Wilson's Disease in Patient with Mildly Elevated Liver Enzymes.1例肝酶轻度升高患者的威尔逊病病例
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Psychosomatics. 2012 Mar-Apr;53(2):175-7. doi: 10.1016/j.psym.2012.01.002.
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