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自闭症谱系障碍的循证医学更新

Evidence Base Update for Autism Spectrum Disorder.

作者信息

Smith Tristram, Iadarola Suzannah

机构信息

a Department of Pediatrics , University of Rochester Medical Center.

出版信息

J Clin Child Adolesc Psychol. 2015;44(6):897-922. doi: 10.1080/15374416.2015.1077448.

DOI:10.1080/15374416.2015.1077448
PMID:26430947
Abstract

This evidence base update examines the level of empirical support for interventions for children with autism spectrum disorder (ASD) younger than 5 years old. It focuses on research published since a previous review in this journal (Rogers & Vismara, 2008 ). We identified psychological or behavioral interventions that had been manualized and evaluated in either (a) experimental or quasi-experimental group studies or (b) systematic reviews of single-subject studies. We extracted data from all studies that met these criteria and were published after the previous review. Interventions were categorized across two dimensions. First, primary theoretical principles included applied behavior analysis (ABA), developmental social-pragmatic (DSP), or both. Second, practice elements included scope (comprehensive or focused), modality (individual intervention with the child, parent training, or classrooms), and intervention targets (e.g., spoken language or alternative and augmentative communication). We classified two interventions as well-established (individual, comprehensive ABA and teacher-implemented, focused ABA + DSP), 3 as probably efficacious (individual, focused ABA for augmentative and alternative communication; individual, focused ABA + DSP; and focused DSP parent training), and 5 as possibly efficacious (individual, comprehensive ABA + DSP; comprehensive ABA classrooms; focused ABA for spoken communication; focused ABA parent training; and teacher-implemented, focused DSP). The evidence base for ASD interventions has grown substantially since 2008. An increasing number of interventions have some empirical support; others are emerging as potentially efficacious. Priorities for future research include improving outcome measures, developing interventions for understudied ASD symptoms (e.g., repetitive behaviors), pinpointing mechanisms of action in interventions, and adapting interventions for implementation with fidelity by community providers.

摘要

本次循证更新考察了针对5岁以下自闭症谱系障碍(ASD)儿童干预措施的实证支持水平。它聚焦于自本期刊上一次综述(罗杰斯和维斯马拉,2008年)以来发表的研究。我们确定了已被手册化并在以下两种研究中得到评估的心理或行为干预措施:(a)实验性或准实验性群组研究,或(b)单病例研究的系统综述。我们从所有符合这些标准且在上次综述之后发表的研究中提取数据。干预措施按两个维度进行分类。首先,主要理论原则包括应用行为分析(ABA)、发展性社会语用学(DSP)或两者兼具。其次,实践要素包括范围(全面或聚焦)、形式(针对儿童的个体干预、家长培训或课堂教学)以及干预目标(例如,口语或替代及辅助沟通)。我们将两种干预措施归类为已确立有效的(个体全面ABA和教师实施的聚焦ABA + DSP),3种归类为可能有效的(针对替代及辅助沟通的个体聚焦ABA;个体聚焦ABA + DSP;以及聚焦DSP家长培训),5种归类为可能有效的(个体全面ABA + DSP;全面ABA课堂教学;针对口语沟通的聚焦ABA;聚焦ABA家长培训;以及教师实施的聚焦DSP)。自2008年以来,ASD干预措施的循证基础有了显著增长。越来越多的干预措施获得了一定的实证支持;其他一些干预措施正逐渐显现出可能有效。未来研究的重点包括改进结果测量方法、针对研究不足的ASD症状(例如重复行为)开发干预措施、明确干预措施的作用机制,以及调整干预措施以便社区服务提供者能够忠实实施。

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