Department of Radiation Oncology, The First Affiliated Hospital of Bengbu Medical University and Tumor Hospital Affiliated to Bengbu Medical University, 287 Changhuai Road, Bengbu, Anhui, 233004, People's Republic of China.
Anhui Province Key Laboratory of Translational Cancer Research Affiliated to Bengbu Medical University, Bengbu, 233004, China.
Radiat Oncol. 2019 Jul 19;14(1):130. doi: 10.1186/s13014-019-1336-7.
Central giant cell granuloma (CGCG) is a rare, non-neoplastic, benign lesion that exhibits expansive and osteolytic biological behavior. CGCG treatment and management is challenging for clinicians.
This report presents the treatment and management of recurrent, aggressive CGCG after surgical resection. After informed consent was obtained, the patient underwent radiotherapy. The lesion size was reduced significantly, with no evidence of recurrence or malignant transformation.
This treatment experience indicates that radiotherapy can be used as a rescue treatment for complicated CGCG involving vital neurovascular structures of the cranial base.
中央性 giant 细胞 肉芽肿（CGCG）是一种罕见的、非肿瘤性的良性病变，具有膨胀性和溶骨性的生物学行为。CGCG 的治疗和管理对临床医生来说具有挑战性。
本报告介绍了手术切除后复发性、侵袭性 CGCG 的治疗和管理。在获得知情同意后，患者接受了放射治疗。病变大小显著缩小，无复发或恶变证据。
这种治疗经验表明，对于涉及颅底重要神经血管结构的复杂 CGCG，放射治疗可以作为一种挽救性治疗方法。
